| Primary information |
|---|
| ID | antitb_1869, |
| Name | 28108242 |
| N-Terminal modification | Mastoparan Polybia-MPII |
| C-Terminal Modification | INWLKLGKMVIDAL |
| Chemical Modification | Free |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Linear |
| Nature | 14 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Isolated from venom of the social wasp Pseudopolybia vespiceps testacea |
| Inhibition Concentration | Mycobacterium abscessus |
| In Vitro/ In vivo | Mycobacterium abscessus subsp. massiliense GO06 |
| Cell Line | 80% inhibition at 12.5 μM |
| Inhibition Concentration | In vitro |
| Sequence | 2017 |
| Cytotoxicity | murine macrophages, human and mouse erythrocytes |
| In vivo Model | 80% inhibition at 12.5 μM |
| Lethal Dose | 50% hemolysis at 24.18 μM and 48.47 μM against mouse and human erythrocytes respectively |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | membrane pore formation |
| Other activities | cell membrane |
| PMID | NA |
| Year of Publication | Antifungal (Candida albicans and Cryptococcus neoformans) and Antibacterial (Staphylococcus aureus) |
Tertiary Structure
(Technique) | Not Predicted), |