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WRSLGRTLLRLSHALKPLARRSGW details |
Primary information | |
---|---|
ID | antitb_1808, |
Name | 21396418 |
N-Terminal modification | Ci-MAM-A24 |
C-Terminal Modification | WRSLGRTLLRLSHALKPLARRSGW |
Chemical Modification | Free |
Linear/Cyclic | Amidation |
Length | None |
Chirality | Linear |
Nature | 24 |
Source | L |
Origin | Cationic |
Species | Protein Derived |
Strain | Derived from immune cells of Ciona intestinalis, |
Inhibition Concentration | Mycobacterium smegmatis |
In Vitro/ In vivo | Mycobacterium smegmatis mc2155 |
Cell Line | 45% bacterial population was killed at 10 μM peptide incubated for 1 hr |
Inhibition Concentration | In vitro |
Sequence | 2011 |
Cytotoxicity | mouse macrophage RAW 264.9 |
In vivo Model | NA |
Lethal Dose | Slight toxic (two-fold decrease in cell viability was observed at 50 μM |
Immune Responce | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1809, |
Name | 21396418 |
N-Terminal modification | Ci-MAM-A25 |
C-Terminal Modification | WRSLGRTLLRLSHALKPLARRSGW |
Chemical Modification | Free |
Linear/Cyclic | Amidation |
Length | None |
Chirality | Linear |
Nature | 24 |
Source | L |
Origin | Cationic |
Species | Protein Derived |
Strain | Derived from immune cells of Ciona intestinalis, |
Inhibition Concentration | Mycobacterium bovis |
In Vitro/ In vivo | Mycobacterium bovis BCG Pasteur (ATCC35734) |
Cell Line | After 24 h, more than 78% killing was observed at 30 μM |
Inhibition Concentration | In vitro |
Sequence | 2011 |
Cytotoxicity | mouse macrophage RAW 264.10 |
In vivo Model | NA |
Lethal Dose | Slight toxic (two-fold decrease in cell viability was observed at 50 μM |
Immune Responce | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |