Primary information |
---|
ID | antitb_1809 |
Peptide Name | Ci-MAM-A25 |
Sequence | WRSLGRTLLRLSHALKPLARRSGW |
N-terminal Modification | Free |
C-terminal Modification | Amidation |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Length | 24 |
Chirality | L |
Nature | Cationic |
Source | Protein Derived |
Origin | Derived from immune cells of Ciona intestinalis, |
Species | Mycobacterium bovis |
Strain | Mycobacterium bovis BCG Pasteur (ATCC35734) |
Inhibition Concentartion | After 24 h, more than 78% killing was observed at 30 μM |
In vitro/In vivo | In vitro |
Cell Line | mouse macrophage RAW 264.10 |
Inhibition Concentartion | NA |
Cytotoxicity | Slight toxic (two-fold decrease in cell viability was observed at 50 μM |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other Activities | NA |
Pubmed ID | 21396418 |
Year of Publication | 2011 |
3-D Structure | NA |