Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0087 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Macrophages | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0087 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Macrophages | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0088 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | NA | O60603.fasta | O60603 | 784 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0088 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | NA | O60603.fasta | O60603 | 784 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0259 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | BALB/c and C57BL/6 mice | Spleen cells | Toll- IL-1R domain | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 17404301 | 2007 | Pubchem Assay |
| PRRID_0259 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | BALB/c and C57BL/6 mice | Spleen cells | Toll- IL-1R domain | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 17404301 | 2007 | Pubchem Assay |
| PRRID_0315 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA binds to vitellogenin with high affinity. | Vitellogenin | Phospholipoglycoprotein | Hexagrammos otakii | Macropahes | NA | NA | NA | NA | Vg is involved in anti-infectious response, functions as an opsonin that can enhance macrophage phagocytosis. | ELISA | 18398466 | 2008 | NA |
| PRRID_0315 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA binds to vitellogenin with high affinity. | Vitellogenin | Phospholipoglycoprotein | Hexagrammos otakii | Macropahes | NA | NA | NA | NA | Vg is involved in anti-infectious response, functions as an opsonin that can enhance macrophage phagocytosis. | ELISA | 18398466 | 2008 | NA |
| PRRID_0316 | Lipoteichoic Acid (LTA) Click for more detail | Bacillus subtilis(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA-treated LEC increases the expression of E-selectin, ICAM-1, and VCAM-1, moreover it induces the expression of CCL2, CCL5, and CCL20 (Cys-Cys motif chemokines) and of CXCL1, CXCL3, CXCL5, CXCL6, and CXCL8 (Cys-X-Cys motif chemokines). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Cultured human lymphatic endothelium (LEC) | LRR | O60603.fasta | O60603 | 784 | It has a immunostimulatory role | ELISA | 18523807 | 2008 | Pubchem Assay |
| PRRID_0316 | Lipoteichoic Acid (LTA) Click for more detail | Bacillus subtilis(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA-treated LEC increases the expression of E-selectin, ICAM-1, and VCAM-1, moreover it induces the expression of CCL2, CCL5, and CCL20 (Cys-Cys motif chemokines) and of CXCL1, CXCL3, CXCL5, CXCL6, and CXCL8 (Cys-X-Cys motif chemokines). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Cultured human lymphatic endothelium (LEC) | LRR | O60603.fasta | O60603 | 784 | It has a immunostimulatory role | ELISA | 18523807 | 2008 | Pubchem Assay |
| PRRID_0317 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | BbFREP can specifically bind LTA. | BbFREP | Multivalent Pattern recognition receptor (PRR) | Amphioxus (Branchiostoma belcheri) | hepatic caecum | fibrinogen-like (FBG) domain | NA | NA | NA | It leads to the bacteriolytic activity via interaction with LTA. | ELISA | 18533266 | 2008 | NA |
| PRRID_0317 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | BbFREP can specifically bind LTA. | BbFREP | Multivalent Pattern recognition receptor (PRR) | Amphioxus (Branchiostoma belcheri) | hepatic caecum | fibrinogen-like (FBG) domain | NA | NA | NA | It leads to the bacteriolytic activity via interaction with LTA. | ELISA | 18533266 | 2008 | NA |
| PRRID_0318 | Lipoteichoic Acid (LTA) Click for more detail | Enterococcus faecalis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Upon exposure to E. faecalis LTA, it produces a high level of tumor necrosis factor-⍺ (TNF-⍺) and nitric oxide (NO). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | RAW 264.7 | NA | Q9QUN7.fasta | Q9QUN7 | 784 | LTA contributes to E. faecalis–induced inflammatory responses. | ELISA | 18634930 | 2008 | Pubchem Assay |
| PRRID_0318 | Lipoteichoic Acid (LTA) Click for more detail | Enterococcus faecalis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Upon exposure to E. faecalis LTA, it produces a high level of tumor necrosis factor-⍺ (TNF-⍺) and nitric oxide (NO). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | RAW 264.7 | NA | Q9QUN7.fasta | Q9QUN7 | 784 | LTA contributes to E. faecalis–induced inflammatory responses. | ELISA | 18634930 | 2008 | Pubchem Assay |
| PRRID_0319 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA induces the Stat1 and Stat3 activation via induction of IRF1/2 and interferon-α production. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macropahges | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It resulted in the antibacterial response. | ELISA | 18652890 | 2008 | Pubchem Assay |
| PRRID_0319 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | LTA induces the Stat1 and Stat3 activation via induction of IRF1/2 and interferon-α production. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macropahges | NA | Q9QUN7.fasta | Q9QUN7 | 784 | It resulted in the antibacterial response. | ELISA | 18652890 | 2008 | Pubchem Assay |
| PRRID_0371 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Odontoblasts | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0371 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Odontoblasts | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0372 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Dental pulp fibroblasts | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0372 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Dental pulp fibroblasts | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0373 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha, IL-1beta and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Immature dendritic cells | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0373 | Lipoteichoic Acid (LTA) Click for more detail | S. aureus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It induces the production of the pro-inflammatory cytokines such as TNF-alpha, IL-1beta and CXCL8. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Immature dendritic cells | LRR | O60603.fasta | O60603 | 784 | It has inflammatory/immune response agianst gram-positive bacteria. | ELISA | 19250704 | 2009 | Pubchem Assay |
| PRRID_0374 | Lipoteichoic Acid (LTA) Click for more detail | S. gordonii (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Stimulation elicits the production of tumour necrosis factor (TNF) and interleukin (IL)-6. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Bone-marrow derived Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | This activation can be attributed to multiple immunostimulatory components present within S. gordonii bacterial cells. | ELISA | 19284500 | 2009 | Pubchem Assay |
| PRRID_0374 | Lipoteichoic Acid (LTA) Click for more detail | S. gordonii (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Stimulation elicits the production of tumour necrosis factor (TNF) and interleukin (IL)-6. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice (Murine) | Bone-marrow derived Dendritic cells | LRR | Q9QUN7.fasta | Q9QUN7 | 784 | This activation can be attributed to multiple immunostimulatory components present within S. gordonii bacterial cells. | ELISA | 19284500 | 2009 | Pubchem Assay |
| PRRID_0652 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins | Toll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It coauses the inflammation | NA | 20740341 | 2010 | NA |
| PRRID_0652 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins | Toll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It coauses the inflammation | NA | 20740341 | 2010 | NA |
| PRRID_0653 | Lipoteichoic Acid (LTA) Click for more detail | E. coli(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Peptidoglycan is the potent activator of the TLR2 | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | C57BL/6 Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUN7.fasta | Q9QUN7 | 784 | Contributes to inflammatory responses induced by orthopaedic wear particles in cell culture and murine models of aseptic loosening of orthopaedic implants | NA | 20729214 | 2010 | Pubchem Assay |
| PRRID_0653 | Lipoteichoic Acid (LTA) Click for more detail | E. coli(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Peptidoglycan is the potent activator of the TLR2 | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | C57BL/6 Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUN7.fasta | Q9QUN7 | 784 | Contributes to inflammatory responses induced by orthopaedic wear particles in cell culture and murine models of aseptic loosening of orthopaedic implants | NA | 20729214 | 2010 | Pubchem Assay |
| PRRID_0654 | Lipoteichoic Acid (LTA) Click for more detail | Lactobacillus acidophilus, Prevotella melaninogenica, P. bivia and Mycobacterium smegmatis (Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Enhanced HIV-1 expression in macrophages | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | It leads to the clearance of the pathogen from the system | NA | 20719993 | 2010 | Pubchem Assay |
| PRRID_0654 | Lipoteichoic Acid (LTA) Click for more detail | Lactobacillus acidophilus, Prevotella melaninogenica, P. bivia and Mycobacterium smegmatis (Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Enhanced HIV-1 expression in macrophages | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | It leads to the clearance of the pathogen from the system | NA | 20719993 | 2010 | Pubchem Assay |
| PRRID_0655 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | Toll-like receptor 2 Arg753Gln (TLR-2 Arg753Gln) | Toll-like receptor (TLR) | FMF patients | monocytes and granulocytes | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | Upregulate inflammation in FMF patients | NA | 20714796 | 2010 | NA |
| PRRID_0655 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | Toll-like receptor 2 Arg753Gln (TLR-2 Arg753Gln) | Toll-like receptor (TLR) | FMF patients | monocytes and granulocytes | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | Upregulate inflammation in FMF patients | NA | 20714796 | 2010 | NA |
| PRRID_0656 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | dendritic cells, macrophages and lymphocytes | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0656 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | dendritic cells, macrophages and lymphocytes | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0657 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector | Toll-like receptor 2/6 (TLR2/6) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It leadsto the secretion of the proinfalmmatory cytokines | NA | 20620129 | 2010 | NA |
| PRRID_0657 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,/TIRAP and aloow the rerutiment of downstream effector | Toll-like receptor 2/6 (TLR2/6) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It leadsto the secretion of the proinfalmmatory cytokines | NA | 20620129 | 2010 | NA |
| PRRID_0658 | Lipoteichoic Acid (LTA) Click for more detail | Micrococcus luteus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | GmCP9 | Pattern recognition receptor (PRR) | Galleria mellonella | hemolymph | NA | NA | NA | NA | It has opsonin activity for the phagocytosis of the microorganisms by hemocytes. | NA | 20519517 | 2010 | NA |
| PRRID_0658 | Lipoteichoic Acid (LTA) Click for more detail | Micrococcus luteus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NA | GmCP9 | Pattern recognition receptor (PRR) | Galleria mellonella | hemolymph | NA | NA | NA | NA | It has opsonin activity for the phagocytosis of the microorganisms by hemocytes. | NA | 20519517 | 2010 | NA |
| PRRID_0659 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It is the responsive PAMP for the FcLec5 | FcLec5 | C type Lectin (CTL/CLR) | Fenneropenaeus chinensis | hepatopancreas | CRD | NA | NA | NA | It elicit the immune response, which leads to the clearance of bacteria | ELISA | 20349323 | 2010 | NA |
| PRRID_0659 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | It is the responsive PAMP for the FcLec5 | FcLec5 | C type Lectin (CTL/CLR) | Fenneropenaeus chinensis | hepatopancreas | CRD | NA | NA | NA | It elicit the immune response, which leads to the clearance of bacteria | ELISA | 20349323 | 2010 | NA |
| PRRID_0928 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0928 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0929 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Myeloid cells, dendritic cells, microglia, astrocytes | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0929 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Myeloid cells, dendritic cells, microglia, astrocytes | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0930 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0930 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0931 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0931 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_1102 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus staphylolyticus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | PcLec5 | C type Lectin (CTL/CLR) | red swamp crayfish (Procambarus clarkii) | hepatopancreas, gills and intestine | carbohydrate recognition domain (CRD) | NA | NA | NA | play important roles in the innate immune system of crustaceans | ELISA | 23989040 | 2013 | NA |
| PRRID_1102 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus staphylolyticus (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | PcLec5 | C type Lectin (CTL/CLR) | red swamp crayfish (Procambarus clarkii) | hepatopancreas, gills and intestine | carbohydrate recognition domain (CRD) | NA | NA | NA | play important roles in the innate immune system of crustaceans | ELISA | 23989040 | 2013 | NA |
| PRRID_1103 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus pyogenes (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | PPL is a glycoprotein with a lipoteichoic acid binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1103 | Lipoteichoic Acid (LTA) Click for more detail | Streptococcus pyogenes (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | PPL is a glycoprotein with a lipoteichoic acid binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1438 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | Cell Surface (Exogenous) | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 24830024 | 2014 | NA |
| PRRID_1438 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | Cell Surface (Exogenous) | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 24830024 | 2014 | NA |
| PRRID_1439 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | Cell Surface (Exogenous) | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 24830024 | 2014 | NA |
| PRRID_1439 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | Cell Surface (Exogenous) | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 24830024 | 2014 | NA |
| PRRID_1440 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | reverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis. | 24828022 | 2014 | Pubchem_assay |
| PRRID_1440 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | reverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis. | 24828022 | 2014 | Pubchem_assay |
| PRRID_1441 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | significant role in the pathogenesis of severe inflammatory responses | Histological analyses, Real-time PCR analysis, Western blotting | 24815695 | 2014 | Pubchem_assay |
| PRRID_1441 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | significant role in the pathogenesis of severe inflammatory responses | Histological analyses, Real-time PCR analysis, Western blotting | 24815695 | 2014 | Pubchem_assay |
| PRRID_1442 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | Possible effect in case of stroke i.e Up-regulation of TLR2 mRNA correlates with severity of ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1442 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | Possible effect in case of stroke i.e Up-regulation of TLR2 mRNA correlates with severity of ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1443 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | O60603.fasta | O60603 | 784 | Possible effect in case of stroke i.e Up-regulation of TLR2 mRNA correlates with severity of ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1443 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | cell surface | O60603.fasta | O60603 | 784 | Possible effect in case of stroke i.e Up-regulation of TLR2 mRNA correlates with severity of ischemia | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1444 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, mast cells and B-lymphocytes | cell surface | Q9EPW9.fasta | Q9EPW9 | 795 | significant role in the pathogenesis of severe inflammatory responses | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1444 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, mast cells and B-lymphocytes | cell surface | Q9EPW9.fasta | Q9EPW9 | 795 | significant role in the pathogenesis of severe inflammatory responses | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1445 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocyte/macrophages, mast cells and B-lymphocytes | cell surface | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1445 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | monocyte/macrophages, mast cells and B-lymphocytes | cell surface | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 24807166 | 2014 | Pubchem_assay |
| PRRID_1446 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Chicken | splenocytes | cell surface | Q9DD78.fasta | Q9DD78 | 793 | TLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c | ELISA | 24797722 | 2014 | Pubchem_assay |
| PRRID_1446 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Chicken | splenocytes | cell surface | Q9DD78.fasta | Q9DD78 | 793 | TLR2 and TLR5 promote cellular activation and the production of cytokines including proinflammatory interleukin (IL)-6, as well as those cytokines that help to initiate and modulate the adaptive immune response, including IL-4, IL-12, and interferon (IFN)-c | ELISA | 24797722 | 2014 | Pubchem_assay |
| PRRID_1447 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus epidermidis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | keratinocytes and mouse skin | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | important for inflammation in the skin following injury | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1447 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus epidermidis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | keratinocytes and mouse skin | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | important for inflammation in the skin following injury | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1448 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus epidermidis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | keratinocytes and mouse skin | cell surface | O60603.fasta | O60603 | 784 | important for inflammation in the skin following injury | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1448 | Lipoteichoic Acid (LTA) Click for more detail | Staphylococcus epidermidis (Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | keratinocytes and mouse skin | cell surface | O60603.fasta | O60603 | 784 | important for inflammation in the skin following injury | NA | 24786223 | 2014 | Pubchem_assay |
| PRRID_1449 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | ischemic brain tissue | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | important for inflammation in the skin following injury | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1449 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | ischemic brain tissue | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | important for inflammation in the skin following injury | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1450 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | ischemic brain tissue | cell surface | O60603.fasta | O60603 | 784 | important for inflammation in the skin following injury | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1450 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | ischemic brain tissue | cell surface | O60603.fasta | O60603 | 784 | important for inflammation in the skin following injury | NA | 24784586 | 2014 | Pubchem_assay |
| PRRID_1451 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771854 | 2014 | Pubchem_assay |
| PRRID_1451 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771854 | 2014 | Pubchem_assay |
| PRRID_1452 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages | cell surface | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771854 | 2014 | Pubchem_assay |
| PRRID_1452 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages | cell surface | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771854 | 2014 | Pubchem_assay |
| PRRID_1453 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771328 | 2014 | Pubchem_assay |
| PRRID_1453 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages | cell surface | Q9QUN7.fasta | Q9QUN7 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771328 | 2014 | Pubchem_assay |
| PRRID_1454 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages | cell surface | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771328 | 2014 | Pubchem_assay |
| PRRID_1454 | Lipoteichoic Acid (LTA) Click for more detail | cell wall of Gram-positive bacteria(Bacteria) | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages | cell surface | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 24771328 | 2014 | Pubchem_assay |
| PRRID_1455 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | extracellular domains of leucine-rich repeat motifs | Q9QUN7.fasta | Q9QUN7 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1455 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | extracellular domains of leucine-rich repeat motifs | Q9QUN7.fasta | Q9QUN7 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1456 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | extracellular domains of leucine-rich repeat motifs | O60603.fasta | O60603 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1456 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells | extracellular domains of leucine-rich repeat motifs | O60603.fasta | O60603 | 784 | significant role in the pathogenesis of severe inflammatory responses | NA | 24754320 | 2014 | Pubchem_assay |
| PRRID_1792 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | elicit innate immune response | MnCTLDcp2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1792 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | elicit innate immune response | MnCTLDcp2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1797 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | elicit innate immune response | MnCTLDcp3 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_1797 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Amphiphile | Natural | elicit innate immune response | MnCTLDcp3 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 26208755 | 2016 | NA |
| PRRID_2297 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NFκB activation and cytokine production | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Human embryonic kidney 293 (HERK 293 ) cells | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2297 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | NFκB activation and cytokine production | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Human embryonic kidney 293 (HERK 293 ) cells | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2298 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Activation of MjSRC. | MjSRC | Scavenger receptor (SR) | Marsupenaeus japonicus | Hemocytes | CCP and MAM domains of MjSRC | A0A1L2DC21.fasta | A0A1L2DC21 | 692 | phagocytosis of pathogenic microbes by macrophage and dendritic cell | Polysacharides binding assay | 28602682 | 2017 | Pubchem_assay |
| PRRID_2298 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Activation of MjSRC. | MjSRC | Scavenger receptor (SR) | Marsupenaeus japonicus | Hemocytes | CCP and MAM domains of MjSRC | A0A1L2DC21.fasta | A0A1L2DC21 | 692 | phagocytosis of pathogenic microbes by macrophage and dendritic cell | Polysacharides binding assay | 28602682 | 2017 | Pubchem_assay |
| PRRID_2299 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Immunostimulant | BjLRP | Low density lipoprotein receptor-related protein (LRP) | B. japonicum | gill, muscle, notochord and testis | LY-EGF-CRD- EGF-CRD | NA | NA | NA | phagocytosis of apoptotic cells | qRT-PCR | 28400271 | 2017 | NA |
| PRRID_2299 | Lipoteichoic Acid (LTA) Click for more detail | Bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | Immunostimulant | BjLRP | Low density lipoprotein receptor-related protein (LRP) | B. japonicum | gill, muscle, notochord and testis | LY-EGF-CRD- EGF-CRD | NA | NA | NA | phagocytosis of apoptotic cells | qRT-PCR | 28400271 | 2017 | NA |