Detailed description page of PRRDB2.0

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PRRID_0652 details
Primary information
PRRIDPRRID_0652
Ligand NameLipoteichoic Acid (LTA)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandActivates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins
Name of receptorToll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt coauses the inflammation
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayNA
Primary information
PRRIDPRRID_0652
Ligand NameLipoteichoic Acid (LTA)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandActivates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins
Name of receptorToll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt coauses the inflammation
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayNA