Primary information |
---|
PRRID | PRRID_0652 |
Ligand Name | Lipoteichoic Acid (LTA) |
Source | Bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Amphiphile |
Occurence | Natural |
Role of Ligand | Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins |
Name of receptor | Toll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | NA |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | It coauses the inflammation |
Assay used | NA |
PMID | 20740341 |
Year of Publication | 2010 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_0652 |
Ligand Name | Lipoteichoic Acid (LTA) |
Source | Bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Amphiphile |
Occurence | Natural |
Role of Ligand | Activates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins |
Name of receptor | Toll-like receptor 2 (TLR2)-Toll-like receptor 6 (TLR6) dimer |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | NA |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | It coauses the inflammation |
Assay used | NA |
PMID | 20740341 |
Year of Publication | 2010 |
Pubchem assay | NA |