Detailed description page of PRRDB2.0

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PRRID_0929 details
Primary information
PRRIDPRRID_0929
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMyeloid cells, dendritic cells, microglia, astrocytes
DomainNA
Sequence of ReceptorQ9Y2C9.fasta
Swiss prot IDQ9Y2C9
Length Of Receptor796
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID21982558
Year of Publication2011
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0929
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMyeloid cells, dendritic cells, microglia, astrocytes
DomainNA
Sequence of ReceptorQ9Y2C9.fasta
Swiss prot IDQ9Y2C9
Length Of Receptor796
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID21982558
Year of Publication2011
Pubchem assayPubchem Assay