Detailed description page of PRRDB2.0

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PRRID_0372 details
Primary information
PRRIDPRRID_0372
Ligand NameLipoteichoic Acid (LTA)
SourceS. aureus (Bacteria)
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandIt induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationDental pulp fibroblasts
DomainLRR
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt has inflammatory/immune response agianst gram-positive bacteria.
Assay usedELISA
PMID19250704
Year of Publication2009
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0372
Ligand NameLipoteichoic Acid (LTA)
SourceS. aureus (Bacteria)
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandIt induces the production of the pro-inflammatory cytokines such as TNF-alpha and CXCL8.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationDental pulp fibroblasts
DomainLRR
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt has inflammatory/immune response agianst gram-positive bacteria.
Assay usedELISA
PMID19250704
Year of Publication2009
Pubchem assayPubchem Assay