Detailed description page of PRRDB2.0

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PRRID_1439 details
Primary information
PRRIDPRRID_1439
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
DomainCell Surface (Exogenous)
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID24830024
Year of Publication2014
Pubchem assayNA
Primary information
PRRIDPRRID_1439
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 2 (TLR2)/Toll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, Myeloid DCs, neutrophils, Mast cells
DomainCell Surface (Exogenous)
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID24830024
Year of Publication2014
Pubchem assayNA