Detailed description page of PRRDB2.0

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PRRID_1445 details
Primary information
PRRIDPRRID_1445
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages, mast cells and B-lymphocytes
Domaincell surface
Sequence of ReceptorQ9Y2C9.fasta
Swiss prot IDQ9Y2C9
Length Of Receptor796
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID24807166
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1445
Ligand NameLipoteichoic Acid (LTA)
SourceGram-positive bacteria
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorToll-like receptor 6 (TLR6)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationmonocyte/macrophages, mast cells and B-lymphocytes
Domaincell surface
Sequence of ReceptorQ9Y2C9.fasta
Swiss prot IDQ9Y2C9
Length Of Receptor796
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID24807166
Year of Publication2014
Pubchem assayPubchem_assay