Detailed description page of PRRDB2.0

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PRRID_0319 details
Primary information
PRRIDPRRID_0319
Ligand NameLipoteichoic Acid (LTA)
SourceS. aureus (Bacteria)
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandLTA induces the Stat1 and Stat3 activation via induction of IRF1/2 and interferon-α production.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMacropahges
DomainNA
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt resulted in the antibacterial response.
Assay usedELISA
PMID18652890
Year of Publication2008
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0319
Ligand NameLipoteichoic Acid (LTA)
SourceS. aureus (Bacteria)
Sequence of ligandC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O
LengthNA
TypeAmphiphile
OccurenceNatural
Role of LigandLTA induces the Stat1 and Stat3 activation via induction of IRF1/2 and interferon-α production.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMacropahges
DomainNA
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt resulted in the antibacterial response.
Assay usedELISA
PMID18652890
Year of Publication2008
Pubchem assayPubchem Assay