Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0004 | Thrombospondin (TSP) Click for more detail | NA | MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGY | 1170 | Glycoprotein | Natural | elicit innate immune response | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Tumor cell lines | NA | P16671.fasta | P16671 | 472 | cellular TSP receptor. | NA | 2435757 | 1987 | Pubchem Assay |
| PRRID_0004 | Thrombospondin (TSP) Click for more detail | NA | MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGY | 1170 | Glycoprotein | Natural | elicit innate immune response | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Tumor cell lines | NA | P16671.fasta | P16671 | 472 | cellular TSP receptor. | NA | 2435757 | 1987 | Pubchem Assay |
| PRRID_0008 | Candida albicans Click for more detail | Candida albicans(fungi) | NA | NA | Whole cell | Natural | Candida albicans binds with human macrophage mannose receptor via carbohydrate recognition-like domains. | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | CRDs | P22897.fasta | P22897 | 1456 | It leads to the receptor-mediated endorytosis of mannose-rich glycoconjugate as well as phagocytosis as well as pinocytisisof yeasts. | Phagocytosis assay | 2258707 | 1990 | Pubchem Assay |
| PRRID_0008 | Candida albicans Click for more detail | Candida albicans(fungi) | NA | NA | Whole cell | Natural | Candida albicans binds with human macrophage mannose receptor via carbohydrate recognition-like domains. | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | CRDs | P22897.fasta | P22897 | 1456 | It leads to the receptor-mediated endorytosis of mannose-rich glycoconjugate as well as phagocytosis as well as pinocytisisof yeasts. | Phagocytosis assay | 2258707 | 1990 | Pubchem Assay |
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0011 | D-mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0013 | L-fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0014 | N-acetylmannosamine Click for more detail | Bacteria | CC(=O)NC1C(C(C(OC1O)CO)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0017 | TPA (tissue plasminogen activator) Click for more detail | Endogenous (others) | PERLQRVVTPVLARTDSEPSGLRGTHKPHRWGCRCGAHRAGARLVGTGMGPGESALGWAARMPPALFPPSHPFHFQRPRDIFKGKGKDREKCQAGLGSGPVGSSGRRGGLYHDGLELGLEVSLPGCWESPGGQEGCSRLREGQVQSPEWGRRWAAVWVVQPDWTEC | 166 | Protein | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0017 | TPA (tissue plasminogen activator) Click for more detail | Endogenous (others) | PERLQRVVTPVLARTDSEPSGLRGTHKPHRWGCRCGAHRAGARLVGTGMGPGESALGWAARMPPALFPPSHPFHFQRPRDIFKGKGKDREKCQAGLGSGPVGSSGRRGGLYHDGLELGLEVSLPGCWESPGGQEGCSRLREGQVQSPEWGRRWAAVWVVQPDWTEC | 166 | Protein | Natural | elicit innate immune response | Mannose receptor | Mannose receptor (MR) | Human | NA | NA | P22897.fasta | P22897 | 1456 | Induces pro-inflammatory cytokine response | NA | 1906888 | 1991 | Pubchem Assay |
| PRRID_0018 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Receptor for Advanced Glycation End-products | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | NA | NA | NA | induces pro-inflammatory cytokine response | NA | 1378843 | 1992 | NA |
| PRRID_0018 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Receptor for Advanced Glycation End-products | Receptor for advanced glycation endproducts (RAGE) | Human | NA | NA | NA | NA | NA | induces pro-inflammatory cytokine response | NA | 1378843 | 1992 | NA |
| PRRID_0023 | Fatty acid Click for more detail | Endogenous (others) | NA | NA | Others | Natural | Immunostimulant | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Heart, intestine, fat, muscle, and testis. | NA | P16671.fasta | P16671 | 472 | increase in oleate transport | NA | 7688729 | 1993 | Pubchem Assay |
| PRRID_0023 | Fatty acid Click for more detail | Endogenous (others) | NA | NA | Others | Natural | Immunostimulant | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Heart, intestine, fat, muscle, and testis. | NA | P16671.fasta | P16671 | 472 | increase in oleate transport | NA | 7688729 | 1993 | Pubchem Assay |
| PRRID_0029 | Thrombospondin (TSP) Click for more detail | Thrombin-induced platelet (others) | MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGY | 1170 | Glycoprotein | Natural | CD36 sequence 139-155 binds TSP and induces a second CD36-binding site, which binds CD36 sequence 93-110 with high affinity. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Platelet Membrane | NA | P16671.fasta | P16671 | 472 | It participates in the adhesive cell interactions. | NA | 7688364 | 1993 | Pubchem Assay |
| PRRID_0029 | Thrombospondin (TSP) Click for more detail | Thrombin-induced platelet (others) | MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGY | 1170 | Glycoprotein | Natural | CD36 sequence 139-155 binds TSP and induces a second CD36-binding site, which binds CD36 sequence 93-110 with high affinity. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Platelet Membrane | NA | P16671.fasta | P16671 | 472 | It participates in the adhesive cell interactions. | NA | 7688364 | 1993 | Pubchem Assay |
| PRRID_0034 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated-LDL is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of LDL. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0034 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated-LDL is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of LDL. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0036 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of AGE proteins. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0036 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of AGE proteins. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0044 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes-derived macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0044 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Monocytes-derived macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0045 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Alveolar macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0045 | surfactant protein-A Click for more detail | Host (Endogenous) (others) | MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF | 248 | Protein | Natural | Carbohydrate moieties of SP-A enhanced adherence of Mycobacterium tuberculosis. | Mannose receptor | Mannose receptor (MR) | Human | Alveolar macrophages | NA | P22897.fasta | P22897 | 1456 | Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis. | NA | 7594549 | 1995 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0050 | lipo-arabinomannan Click for more detail | mycobacteria (Mycobacterium tuberculosis; Erdman strain) (Bacteria) | CCC(CO)NCCNC(CC)CO | NA | Glycolipid | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | Human | Macrophages | NA | P22897.fasta | P22897 | 1456 | NA | Chromatographic analyses | 8906835 | 1996 | Pubchem Assay |
| PRRID_0060 | Advanced Glycation End-products (AGE)-BSA Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0060 | Advanced Glycation End-products (AGE)-BSA Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0061 | Advanced Glycation End-products (AGE)-Hb Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0061 | Advanced Glycation End-products (AGE)-Hb Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0066 | Apoptotic cells Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | NA | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Immature dendritic cells | NA | P16671.fasta | P16671 | 472 | It leads to the phagocytosis of the apoptotic cells as well as Cross-present Antigens to Cytotoxic T Lymphocytes. | NA | 9763615 | 1998 | Pubchem Assay |
| PRRID_0066 | Apoptotic cells Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | NA | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Immature dendritic cells | NA | P16671.fasta | P16671 | 472 | It leads to the phagocytosis of the apoptotic cells as well as Cross-present Antigens to Cytotoxic T Lymphocytes. | NA | 9763615 | 1998 | Pubchem Assay |
| PRRID_0067 | Gram-negative Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0067 | Gram-negative Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0068 | High Density Lipoprotein (HDL) Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins LDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0068 | High Density Lipoprotein (HDL) Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins LDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0069 | Low Density Lipoprotein (LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins HDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0069 | Low Density Lipoprotein (LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins HDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0072 | Very Low Density Lipoprotein (VLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins VLDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0072 | Very Low Density Lipoprotein (VLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | CD36 is a high affinity receptor for the native lipoproteins VLDL. | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | Monocytes/Macrophages | NA | P16671.fasta | P16671 | 472 | Lipoprotein binding assay | NA | 9555943 | 1998 | Pubchem Assay |
| PRRID_0073 | Gram-positive bacteria Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0073 | Gram-positive bacteria Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0074 | Peptidoglycan (PGN) Click for more detail | S. aureus (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Peptidoglycan recognition by TLR 2 leads to the activation of NF-KB, which leads to the secretion of proinflammatory cytokines. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | TLR2 is responsible for recognzing the cell wall components of the gram-positive bacteria and induces the respective immune response. | EMSA | 10384090 | 1999 | Pubchem Assay |
| PRRID_0074 | Peptidoglycan (PGN) Click for more detail | S. aureus (Bacteria) | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Peptidoglycan recognition by TLR 2 leads to the activation of NF-KB, which leads to the secretion of proinflammatory cytokines. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | TLR2 is responsible for recognzing the cell wall components of the gram-positive bacteria and induces the respective immune response. | EMSA | 10384090 | 1999 | Pubchem Assay |
| PRRID_0075 | pneumolysin Click for more detail | S. pneumoniae (Bacteria) | MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND | 471 | NA | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | ytokine induction is mediated through NF-kappaB activation | NA | 10411278 | 1999 | Pubchem Assay |
| PRRID_0075 | pneumolysin Click for more detail | S. pneumoniae (Bacteria) | MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND | 471 | NA | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | ytokine induction is mediated through NF-kappaB activation | NA | 10411278 | 1999 | Pubchem Assay |
| PRRID_0076 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0076 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0078 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0078 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0079 | Chondroitin Sulfates A Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0079 | Chondroitin Sulfates A Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0080 | Chondroitin Sulfates B Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0080 | Chondroitin Sulfates B Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0083 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U373 human astrocytoma cells | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0083 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U373 human astrocytoma cells | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0084 | Heat-shock proteins 60 Click for more detail | Endogenous (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | immunostimulantt | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | induction of TNF-alpha and NO formation | NA | 10623794 | 2000 | Pubchem Assay |
| PRRID_0084 | Heat-shock proteins 60 Click for more detail | Endogenous (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | immunostimulantt | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | induction of TNF-alpha and NO formation | NA | 10623794 | 2000 | Pubchem Assay |
| PRRID_0085 | High Density Lipoprotein (HDL) Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0085 | High Density Lipoprotein (HDL) Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0087 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Macrophages | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0087 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Macrophages | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0088 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | NA | O60603.fasta | O60603 | 784 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0088 | Lipoteichoic Acid (LTA) Click for more detail | Gram-positive bacteria | C(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)O | NA | Amphiphile | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Macrophages | NA | O60603.fasta | O60603 | 784 | production of pro-inflammatory cytokines | ELISA | 11095740 | 2000 | Pubchem Assay |
| PRRID_0089 | Murabutide Click for more detail | MDP (others) | CCCCOC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptidoglycan | Synthetic | Stimulation with murabutide leads to the significant release of TNF-a, IL-6, MIP-1a, MIP-1b, RANTES and high levels of beta-chemokines. | NA | NA | Human | Monocytes-derived macrophages and dendritic cells | NA | NA | NA | NA | Murabutide has the capacity to enhance nonspecific resistance against viral infections and to target cells of the reticuloendothelial system. | ELISA | 10933686 | 2000 | NA |
| PRRID_0089 | Murabutide Click for more detail | MDP (others) | CCCCOC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C | NA | Peptidoglycan | Synthetic | Stimulation with murabutide leads to the significant release of TNF-a, IL-6, MIP-1a, MIP-1b, RANTES and high levels of beta-chemokines. | NA | NA | Human | Monocytes-derived macrophages and dendritic cells | NA | NA | NA | NA | Murabutide has the capacity to enhance nonspecific resistance against viral infections and to target cells of the reticuloendothelial system. | ELISA | 10933686 | 2000 | NA |
| PRRID_0092 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | Pubchem Assay |
| PRRID_0092 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | Pubchem Assay |
| PRRID_0093 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0093 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | It binds to the CD36 with high affinity | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | CHO cells | NA | P16671.fasta | P16671 | 472 | CD36 mediates the endocytic uptake and subsequent intracellular degradation. | Cellular assay | 11035013 | 2000 | Pubchem Assay |
| PRRID_0095 | Sulfated blood group chains Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0095 | Sulfated blood group chains Click for more detail | Host (Endogenous) (others) | NA | NA | Carbohydrate | Natural | Chondroitin Sulfates A binds to mannose receptor via a membrane-distal cysteine-rich domain (Cys-MR). | Cys-MR | Mannose receptor (MR) | Human | Spleenocytes | carbohydrate-recognition domain (CRD) | NA | NA | NA | The Cysteine-rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates A and B and Sulfated Oligosaccharides of Blood Group. | NA | 10748230 | 2000 | NA |
| PRRID_0099 | dsRNA Click for more detail | Type I Lang mammalian reovirus (virus) | NA | NA | Nucleic Acid | Natural | It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12. | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | (HEK293 t cells) | NA | O15455.fasta | O15455 | 904 | IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens. | EMSA | 11607032 | 2001 | Pubchem Assay |
| PRRID_0099 | dsRNA Click for more detail | Type I Lang mammalian reovirus (virus) | NA | NA | Nucleic Acid | Natural | It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12. | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | (HEK293 t cells) | NA | O15455.fasta | O15455 | 904 | IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens. | EMSA | 11607032 | 2001 | Pubchem Assay |
| PRRID_0101 | Heat-shock proteins 60 Click for more detail | Human (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | HSP60 activate the stress activated protein kinases p38 and JNK1/2, the mitogen activated protein kinases ERK1/2, and the I-kB kinase (IKK). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | It has the role in immuno inflammation. | Luciferase reporter assay | 11402040 | 2001 | Pubchem Assay |
| PRRID_0101 | Heat-shock proteins 60 Click for more detail | Human (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | HSP60 activate the stress activated protein kinases p38 and JNK1/2, the mitogen activated protein kinases ERK1/2, and the I-kB kinase (IKK). | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O60603.fasta | O60603 | 784 | It has the role in immuno inflammation. | Luciferase reporter assay | 11402040 | 2001 | Pubchem Assay |
| PRRID_0102 | Heat-shock proteins 60 Click for more detail | Human (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | HSP60 activate the stress activated protein kinases p38 and JNK1/2, the mitogen activated protein kinases ERK1/2, and the I-kB kinase (IKK). | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | Luciferase reporter assay | 11402040 | 2001 | Pubchem Assay |
| PRRID_0102 | Heat-shock proteins 60 Click for more detail | Human (others) | MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF | 573 | Protein | Natural | HSP60 activate the stress activated protein kinases p38 and JNK1/2, the mitogen activated protein kinases ERK1/2, and the I-kB kinase (IKK). | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Fibroblasts | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | Luciferase reporter assay | 11402040 | 2001 | Pubchem Assay |
| PRRID_0108 | Others Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | Immunostimulant | LOX1 | Lectins | Human | NA | NA | P78380.fasta | P78380 | 273 | NA | ELISA | 11290792 | 2001 | Pubchem Assay |
| PRRID_0108 | Others Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | Immunostimulant | LOX1 | Lectins | Human | NA | NA | P78380.fasta | P78380 | 273 | NA | ELISA | 11290792 | 2001 | Pubchem Assay |
| PRRID_0109 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Synthetic | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. | ELISA | 11701468 | 2001 | Pubchem Assay |
| PRRID_0109 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Synthetic | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. | ELISA | 11701468 | 2001 | Pubchem Assay |
| PRRID_0110 | plasmodium-infected erythrocytes Click for more detail | Others | NA | NA | Others | Natural | immunostimulant | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | thrombospondin | NA | P16671.fasta | P16671 | 472 | nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production | NA | 11323673 | 2001 | Pubchem Assay |
| PRRID_0110 | plasmodium-infected erythrocytes Click for more detail | Others | NA | NA | Others | Natural | immunostimulant | cluster of differentiation 36 (CD36) | Pattern recognition receptor (PRR) | Human | thrombospondin | NA | P16671.fasta | P16671 | 472 | nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production | NA | 11323673 | 2001 | Pubchem Assay |
| PRRID_0111 | polyinosinic-polycytidylic acid [poly(I:C)] Click for more detail | NA | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12. | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | (HEK293 t cells) | NA | O15455.fasta | O15455 | 904 | IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens. | EMSA | 11607032 | 2001 | Pubchem Assay |
| PRRID_0111 | polyinosinic-polycytidylic acid [poly(I:C)] Click for more detail | NA | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | It induces the activation of NF-kappaB and secretion of type I IFNs, IFN-alpha and IFN-beta and cytokines IL-6 and IL-12. | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | (HEK293 t cells) | NA | O15455.fasta | O15455 | 904 | IFNs inhibit virus replication, IL-6 and IL-12, which are also induced by bacterial infections, elicit cytotoxic responses needed for elimination of intracellular pathogens. | EMSA | 11607032 | 2001 | Pubchem Assay |
| PRRID_0112 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE behaves as al ligand for BLOX-1. | Lectin-like oxidized LDLreceptor 1 | C type Lectin (CTL/CLR) | Human | Endothelial cells | NA | P78380.fasta | P78380 | 273 | Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products. | Endocytic degradation assays | 11821070 | 2002 | Pubchem Assay |
| PRRID_0112 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE behaves as al ligand for BLOX-1. | Lectin-like oxidized LDLreceptor 1 | C type Lectin (CTL/CLR) | Human | Endothelial cells | NA | P78380.fasta | P78380 | 273 | Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products. | Endocytic degradation assays | 11821070 | 2002 | Pubchem Assay |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0114 | alpha-methylmannoside Click for more detail | Bacteria | COC1C(C(C(C(O1)CO)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0117 | Fucose Click for more detail | Bacteria | CC(C(C(C(C=O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0118 | glucose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Endo180 | Mannose receptor (MR) | Human | NA | lectin-like domains | Q9UBG0.fasta | Q9UBG0 | 1479 | NA | Sugar-Binding assay | 12399458 | 2002 | Pubchem Assay |
| PRRID_0119 | GP96 Click for more detail | Human (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | It results in activation of nuclear factor kappaB-driven reporter genes, and mitogen- and stress-activated protein kinases and induces I | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Embryonic Kidney Fibroblasts— 293T | LRR | O60603.fasta | O60603 | 784 | Gp96 has the ability to induce specific immune responses against tumors and pathogens | Luciferase reporter assay | 11912201 | 2002 | Pubchem Assay |
| PRRID_0119 | GP96 Click for more detail | Human (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | It results in activation of nuclear factor kappaB-driven reporter genes, and mitogen- and stress-activated protein kinases and induces I | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Embryonic Kidney Fibroblasts— 293T | LRR | O60603.fasta | O60603 | 784 | Gp96 has the ability to induce specific immune responses against tumors and pathogens | Luciferase reporter assay | 11912201 | 2002 | Pubchem Assay |
| PRRID_0120 | GP96 Click for more detail | Human (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | It results in activation of nuclear factor kappaB-driven reporter genes, and mitogen- and stress-activated protein kinases and induces I | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Embryonic Kidney Fibroblasts— 293T | LRR | O00206.fasta | O00206 | 839 | Gp96 has the ability to induce specific immune responses against tumors and pathogens | Luciferase reporter assay | 11912201 | 2002 | Pubchem Assay |
| PRRID_0120 | GP96 Click for more detail | Human (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | It results in activation of nuclear factor kappaB-driven reporter genes, and mitogen- and stress-activated protein kinases and induces I | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Embryonic Kidney Fibroblasts— 293T | LRR | O00206.fasta | O00206 | 839 | Gp96 has the ability to induce specific immune responses against tumors and pathogens | Luciferase reporter assay | 11912201 | 2002 | Pubchem Assay |