Detailed description page of PRRDB2.0

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PRRID_0075 details
Primary information
PRRIDPRRID_0075
Ligand Namepneumolysin
SourceS. pneumoniae (Bacteria)
Sequence of ligandMANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND
Length471
TypeNA
OccurenceNatural
Role of LigandImmunostimulant
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionytokine induction is mediated through NF-kappaB activation
Assay usedNA
PMID10411278
Year of Publication1999
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0075
Ligand Namepneumolysin
SourceS. pneumoniae (Bacteria)
Sequence of ligandMANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQLKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND
Length471
TypeNA
OccurenceNatural
Role of LigandImmunostimulant
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionytokine induction is mediated through NF-kappaB activation
Assay usedNA
PMID10411278
Year of Publication1999
Pubchem assayPubchem Assay