Detailed description page of PRRDB2.0
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PRRID_0109 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0109 |
| Ligand Name | oxidized LDL (OxLDL) |
| Source | Endogenous (others) |
| Sequence of ligand | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 |
| Length | NA |
| Type | Lipoprotein |
| Occurence | Synthetic |
| Role of Ligand | Ox-LDL binds with SR-PSOX with high affinity. |
| Name of receptor | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) |
| Type of receptor | Scavenger receptor (SR) |
| Source | Human |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | Q9H2A7.fasta |
| Swiss prot ID | Q9H2A7 |
| Length Of Receptor | 254 |
| Function | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. |
| Assay used | ELISA |
| PMID | 11701468 |
| Year of Publication | 2001 |
| Pubchem assay | Pubchem Assay |
| Primary information | |
|---|---|
| PRRID | PRRID_0109 |
| Ligand Name | oxidized LDL (OxLDL) |
| Source | Endogenous (others) |
| Sequence of ligand | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 |
| Length | NA |
| Type | Lipoprotein |
| Occurence | Synthetic |
| Role of Ligand | Ox-LDL binds with SR-PSOX with high affinity. |
| Name of receptor | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) |
| Type of receptor | Scavenger receptor (SR) |
| Source | Human |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | Q9H2A7.fasta |
| Swiss prot ID | Q9H2A7 |
| Length Of Receptor | 254 |
| Function | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. |
| Assay used | ELISA |
| PMID | 11701468 |
| Year of Publication | 2001 |
| Pubchem assay | Pubchem Assay |