| Primary information |
|---|
| PRRID | PRRID_0083 |
| Ligand Name | ER-112022 |
| Source | lipid A derivative (others) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipid |
| Occurence | Synthetic |
| Role of Ligand | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | U373 human astrocytoma cells |
| Domain | LRR |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | It has the role in immuno inflammation. |
| Assay used | ELISA |
| PMID | 11032843 |
| Year of Publication | 2000 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0083 |
| Ligand Name | ER-112022 |
| Source | lipid A derivative (others) |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
| Length | NA |
| Type | Lipid |
| Occurence | Synthetic |
| Role of Ligand | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | U373 human astrocytoma cells |
| Domain | LRR |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | It has the role in immuno inflammation. |
| Assay used | ELISA |
| PMID | 11032843 |
| Year of Publication | 2000 |
| Pubchem assay | Pubchem Assay |