Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0005 | Fucoidan Click for more detail | NA | CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Bovine | smooth muscle cells | NA | NA | NA | NA | NA | NA | 3397384 | 1988 | NA |
| PRRID_0005 | Fucoidan Click for more detail | NA | CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O | NA | Carbohydrate | Natural | elicit innate immune response | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Bovine | smooth muscle cells | NA | NA | NA | NA | NA | NA | 3397384 | 1988 | NA |
| PRRID_0009 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0009 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0010 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0010 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0012 | Fucoidan Click for more detail | NA | CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O | NA | Carbohydrate | Natural | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. | Scavenger receptor class A | Scavenger receptor (SR) | Macrophage cell line (RAW264) | Macrophages | NA | NA | NA | NA | It leads to polyanion-induced macrophage plasminogen activation. | Functional assay for plasmin | 1658006 | 1991 | NA |
| PRRID_0012 | Fucoidan Click for more detail | NA | CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O | NA | Carbohydrate | Natural | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. | Scavenger receptor class A | Scavenger receptor (SR) | Macrophage cell line (RAW264) | Macrophages | NA | NA | NA | NA | It leads to polyanion-induced macrophage plasminogen activation. | Functional assay for plasmin | 1658006 | 1991 | NA |
| PRRID_0015 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0015 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 2300204 | 1991 | NA |
| PRRID_0016 | Phorbol myristate acetate (PMA) Click for more detail | NA | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C | NA | Carbohydrate | Natural | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. | Scavenger receptor class A | Scavenger receptor (SR) | Macrophage cell line (RAW264) | Macrophages | NA | NA | NA | NA | It leads to polyanion-induced macrophage plasminogen activation. | Functional assay for plasmin | 1658006 | 1991 | NA |
| PRRID_0016 | Phorbol myristate acetate (PMA) Click for more detail | NA | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C | NA | Carbohydrate | Natural | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. | Scavenger receptor class A | Scavenger receptor (SR) | Macrophage cell line (RAW264) | Macrophages | NA | NA | NA | NA | It leads to polyanion-induced macrophage plasminogen activation. | Functional assay for plasmin | 1658006 | 1991 | NA |
| PRRID_0019 | Asbestos Click for more detail | Crocidolite(others) | O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2] | NA | Silicate Mineral | Natural | Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor. | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | It mediates the physiological and pathological interactions of the particles with alveolar macrophages. | Solid-phase bead-binding assay | 8381434 | 1992 | NA |
| PRRID_0019 | Asbestos Click for more detail | Crocidolite(others) | O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2] | NA | Silicate Mineral | Natural | Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor. | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | It mediates the physiological and pathological interactions of the particles with alveolar macrophages. | Solid-phase bead-binding assay | 8381434 | 1992 | NA |
| PRRID_0020 | Asbestos Click for more detail | Crocidolite(others) | O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2] | NA | Silicate Mineral | Natural | Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor. | Scavenger receptor A II | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | It mediates the physiological and pathological interactions of the particles with alveolar macrophages. | Solid-phase bead-binding assay | 8381434 | 1992 | NA |
| PRRID_0020 | Asbestos Click for more detail | Crocidolite(others) | O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2] | NA | Silicate Mineral | Natural | Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor. | Scavenger receptor A II | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | It mediates the physiological and pathological interactions of the particles with alveolar macrophages. | Solid-phase bead-binding assay | 8381434 | 1992 | NA |
| PRRID_0027 | poly(I:G) Click for more detail | synthetic oligonucleotide (others) | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8429030 | 1993 | NA |
| PRRID_0027 | poly(I:G) Click for more detail | synthetic oligonucleotide (others) | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8429030 | 1993 | NA |
| PRRID_0028 | poly(I:G) Click for more detail | synthetic oligonucleotide (others) | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8429030 | 1993 | NA |
| PRRID_0028 | poly(I:G) Click for more detail | synthetic oligonucleotide (others) | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8429030 | 1993 | NA |
| PRRID_0031 | maleylated BSA Click for more detail | NA | MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA | 607 | Protein | Natural | Immunostimulant | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary (CHO) cell | NA | NA | NA | NA | NA | ELISA | 7520436 | 1994 | NA |
| PRRID_0031 | maleylated BSA Click for more detail | NA | MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA | 607 | Protein | Natural | Immunostimulant | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary (CHO) cell | NA | NA | NA | NA | NA | ELISA | 7520436 | 1994 | NA |
| PRRID_0032 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | dSR-C1 | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0032 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | dSR-C1 | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0033 | Acetylated LDL Click for more detail | NA | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated LDL is a potent ligand for MARCO | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0033 | Acetylated LDL Click for more detail | NA | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated LDL is a potent ligand for MARCO | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0034 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated-LDL is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of LDL. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0034 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Acetylated-LDL is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of LDL. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0036 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of AGE proteins. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0036 | Advanced Glycation End Products (AGE) Click for more detail | Host (Endogenous) (others) | NA | NA | Protein | Natural | AGE is a potent activator of MSR. | Macrophage Scavenger Receptor (MSR) | Scavenger receptor (SR) | Human | Macrophages | NA | P21757.fasta | P21757 | 451 | The MSR mediates the endocytic uptake and degradation of AGE proteins. | NA | 7607209 | 1995 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0037 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | E.coli binds with MARCO with high affinity. | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0038 | Laminarin Click for more detail | laminaria (others) | C(C1C(C(C(C(O1)O)O)OC2C(C(C(C(O2)CO)O)OC3C(C(C(C(O3)CO)O)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Scavenger receptor C-1 (SR-C1) | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0038 | Laminarin Click for more detail | laminaria (others) | C(C1C(C(C(C(O1)O)O)OC2C(C(C(C(O2)CO)O)OC3C(C(C(C(O3)CO)O)O)O)O)O)O | NA | Carbohydrate | Natural | Immunostimulant | Scavenger receptor C-1 (SR-C1) | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0042 | poly D-glutamic acid Click for more detail | synthetic polypeptyide (others) | C(CC(=O)O)C(C(=O)O)N | NA | Peptide | Natural | Immunostimulant | Scavenger receptor C-1 (SR-C1) | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0042 | poly D-glutamic acid Click for more detail | synthetic polypeptyide (others) | C(CC(=O)O)C(C(=O)O)N | NA | Peptide | Natural | Immunostimulant | Scavenger receptor C-1 (SR-C1) | Scavenger receptor (SR) | Drosophila melanogaster | NA | two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains | NA | NA | NA | NA | NA | 7732030 | 1995 | NA |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0043 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | S. aureus binds with MARCO with high affinity | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Mice | Macrophages | NA | A2RT24.fasta | A2RT24 | 518 | It plays a role in immunological reactions. | Immunoprecipitation | 7867067 | 1995 | Pubchem Assay |
| PRRID_0046 | amyloid beta peptide Click for more detail | Endogenous (others) | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Peptide | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8816718 | 1996 | NA |
| PRRID_0046 | amyloid beta peptide Click for more detail | Endogenous (others) | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Peptide | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8816718 | 1996 | NA |
| PRRID_0047 | amyloid beta peptide Click for more detail | Endogenous (others) | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Peptide | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8816718 | 1996 | NA |
| PRRID_0047 | amyloid beta peptide Click for more detail | Endogenous (others) | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN | 770 | Peptide | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8816718 | 1996 | NA |
| PRRID_0048 | Apoptotic thymocytes Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation. | Scavenger receptor class A | Scavenger receptor (SR) | Mice | Thymic macrophages | NA | Q68EF1.fasta | Q68EF1 | 474 | SR-A may play a role in the clearance of dying cells in the thymus. | Phagocytosis Assay | 8901603 | 1996 | Pubchem Assay |
| PRRID_0048 | Apoptotic thymocytes Click for more detail | Host (Endogenous) (others) | NA | NA | Whole cell | Natural | Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation. | Scavenger receptor class A | Scavenger receptor (SR) | Mice | Thymic macrophages | NA | Q68EF1.fasta | Q68EF1 | 474 | SR-A may play a role in the clearance of dying cells in the thymus. | Phagocytosis Assay | 8901603 | 1996 | Pubchem Assay |
| PRRID_0049 | Fractionated [(3)H]heparin Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O | NA | Glycosaminoglycan | Natural | Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Rat | Kupffer cells | NA | NA | NA | NA | Adsorptive endocytosis of polypeptides and phagocytosis. | NA | 8860963 | 1996 | NA |
| PRRID_0049 | Fractionated [(3)H]heparin Click for more detail | Host (Endogenous) (others) | CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O | NA | Glycosaminoglycan | Natural | Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | Rat | Kupffer cells | NA | NA | NA | NA | Adsorptive endocytosis of polypeptides and phagocytosis. | NA | 8860963 | 1996 | NA |
| PRRID_0052 | maleylated BSA Click for more detail | NA | MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA | 607 | Protein | Natural | immunostimulantt | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 8560269 | 1996 | NA |
| PRRID_0052 | maleylated BSA Click for more detail | NA | MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA | 607 | Protein | Natural | immunostimulantt | Scavenger receptor B-1 (SR-B1) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 8560269 | 1996 | NA |
| PRRID_0055 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor expressed by endothelial cells 1 | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary cells | Lectin-like domains | NA | NA | NA | NA | ELISA | 9395444 | 1997 | NA |
| PRRID_0055 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor expressed by endothelial cells 1 | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary cells | Lectin-like domains | NA | NA | NA | NA | ELISA | 9395444 | 1997 | NA |
| PRRID_0057 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0057 | Acetylated LDL Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0059 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0059 | Advanced Glycation End Products (AGE) Click for more detail | Endogenous (others) | NA | NA | Others | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0060 | Advanced Glycation End-products (AGE)-BSA Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0060 | Advanced Glycation End-products (AGE)-BSA Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0061 | Advanced Glycation End-products (AGE)-Hb Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0061 | Advanced Glycation End-products (AGE)-Hb Click for more detail | Human (others) | NA | NA | Protein | Natural | AGE-modified proteins binds to scavenger receptor with high affinity. | Scavenger receptor class A | Scavenger receptor (SR) | Human | hepatic sinusoidal Kupffer and endothelial cells | NA | NA | NA | NA | AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs. | NA | 9065778 | 1997 | NA |
| PRRID_0062 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor expressed by endothelial cells 1 | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary cells | Lectin-like domains | NA | NA | NA | NA | ELISA | 9395444 | 1997 | NA |
| PRRID_0062 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Immunostimulant | Scavenger receptor expressed by endothelial cells 1 | Scavenger receptor (SR) | Chinese Hamster | Chinese hamster ovary cells | Lectin-like domains | NA | NA | NA | NA | ELISA | 9395444 | 1997 | NA |
| PRRID_0064 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0064 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | elicit innate immune response | Scavenger receptor A II | Scavenger receptor (SR) | Mice | Macrophages | NA | Q08857.fasta | Q08857 | 472 | production of pro-inflammatory cytokines | NA | 9069289 | 1997 | Pubchem Assay |
| PRRID_0065 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | AcLDL pretreatment increased expression of macrosialin | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0065 | Acetylated LDL Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | AcLDL pretreatment increased expression of macrosialin | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0067 | Gram-negative Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0067 | Gram-negative Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0070 | Minimally oxidized LDL (MM-LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0070 | Minimally oxidized LDL (MM-LDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0071 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | OxLDL pretreatment increased expression of macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0071 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | OxLDL pretreatment increased expression of macrosialin. | Microsialin | Scavenger receptor (SR) | Mice | Peritoneal macrophages | NA | A0A0R4J1C8.fasta | A0A0R4J1C8 | 335 | It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages. | Endocytic degradation assays | 9598839 | 1998 | Pubchem Assay |
| PRRID_0073 | Gram-positive bacteria Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0073 | Gram-positive bacteria Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | NA | Macrophage receptor with collagenous structure (MARCO) | Scavenger receptor (SR) | Human | Macrophages | cysteine-rich motif (SRCR) | Q9UEW3.fasta | Q9UEW3 | 520 | MARCO is likely to play a role in host defense. | NA | 9468508 | 1998 | Pubchem Assay |
| PRRID_0091 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | PMA treated THP-1 cells | Macrophages | NA | NA | NA | NA | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | NA |
| PRRID_0091 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | PMA treated THP-1 cells | Macrophages | NA | NA | NA | NA | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | NA |
| PRRID_0092 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | Pubchem Assay |
| PRRID_0092 | oxidized LDL (OxLDL) Click for more detail | Host (Endogenous) (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Natural | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger receptor PSOX (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis. | ELISA | 11060282 | 2000 | Pubchem Assay |
| PRRID_0094 | Silica Click for more detail | Environment particle (others) | O=[Si]=O | NA | Chemical Compunds | Natural | Silica particulates bind to the scavenger receptor and initiate apoptosis | Scavenger receptor A II | Scavenger receptor (SR) | Chinese Hamster | Macrophages | NA | NA | NA | NA | SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis. | ELISA | 10637133 | 2000 | NA |
| PRRID_0094 | Silica Click for more detail | Environment particle (others) | O=[Si]=O | NA | Chemical Compunds | Natural | Silica particulates bind to the scavenger receptor and initiate apoptosis | Scavenger receptor A II | Scavenger receptor (SR) | Chinese Hamster | Macrophages | NA | NA | NA | NA | SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis. | ELISA | 10637133 | 2000 | NA |
| PRRID_0104 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | Scavenger receptor class A | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0104 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | Scavenger receptor class A | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0106 | NA Click for more detail | Gram-negative bacteria | NA | NA | Others | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0106 | NA Click for more detail | Gram-negative bacteria | NA | NA | Others | Natural | Immunostimulant | Scavenger receptor A I (SR-A I) | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0107 | NA Click for more detail | Gram-negative bacteria | NA | NA | Others | Natural | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0107 | NA Click for more detail | Gram-negative bacteria | NA | NA | Others | Natural | Immunostimulant | Scavenger receptor A II | Scavenger receptor (SR) | NA | NA | NA | NA | NA | NA | NA | NA | 1852209 | 2001 | NA |
| PRRID_0109 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Synthetic | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. | ELISA | 11701468 | 2001 | Pubchem Assay |
| PRRID_0109 | oxidized LDL (OxLDL) Click for more detail | Endogenous (others) | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1 | NA | Lipoprotein | Synthetic | Ox-LDL binds with SR-PSOX with high affinity. | Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX) | Scavenger receptor (SR) | Human | Macrophages | NA | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation. | ELISA | 11701468 | 2001 | Pubchem Assay |
| PRRID_0133 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Scavenger receptor class B, type I (SR-BI) | Scavenger receptor (SR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q06BI8.fasta | Q06BI8 | 494 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0133 | Hypochlorite modified HDL Click for more detail | Host (Endogenous) (others) | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C | NA | Lipoprotein | Natural | It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1). | Scavenger receptor class B, type I (SR-BI) | Scavenger receptor (SR) | Mice (Murine) | CHO Cells—ldlA cells | NA | Q06BI8.fasta | Q06BI8 | 494 | It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport. | NA | 12070141 | 2002 | Pubchem Assay |
| PRRID_0144 | Others Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | Immunostimulant | Fasciclin EGF-like laminin-typeEGF-like and link domain-containing scavenger receptor 1/2 | Scavenger receptor (SR) | Chinese Hamster | Spleen and lymph node | fasciclin, EGF-like, laminin-type EGF-like, and link domain | NA | NA | NA | NA | ELISA | 12077138 | 2002 | NA |
| PRRID_0144 | Others Click for more detail | Gram-positive and negative bacteria | NA | NA | NA | Natural | Immunostimulant | Fasciclin EGF-like laminin-typeEGF-like and link domain-containing scavenger receptor 1/2 | Scavenger receptor (SR) | Chinese Hamster | Spleen and lymph node | fasciclin, EGF-like, laminin-type EGF-like, and link domain | NA | NA | NA | NA | ELISA | 12077138 | 2002 | NA |
| PRRID_0165 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0165 | Escherichia coli Click for more detail | E. coli(Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0168 | gp96 (GRP94) Click for more detail | Host (Endogenous) (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC | Scavenger receptor class A | Scavenger receptor (SR) | C57/BL6 mice | macrophages and dendritic cells | NA | Q08857.fasta | Q08857 | 472 | serves a primary role in gp96 and calreticulin recognition and internalization | NA | 14609958 | 2003 | Pubchem Assay |
| PRRID_0168 | gp96 (GRP94) Click for more detail | Host (Endogenous) (others) | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL | 803 | Protein | Natural | elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC | Scavenger receptor class A | Scavenger receptor (SR) | C57/BL6 mice | macrophages and dendritic cells | NA | Q08857.fasta | Q08857 | 472 | serves a primary role in gp96 and calreticulin recognition and internalization | NA | 14609958 | 2003 | Pubchem Assay |
| PRRID_0187 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0187 | Staphylococcus aureus Click for more detail | S. aureus (Bacteria) | NA | NA | Whole cell | Natural | The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16. | Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16) | Scavenger receptor (SR) | Human | Macrophages and Dendritic cells | Chemokine domain | Q9H2A7.fasta | Q9H2A7 | 254 | SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis. | ELISA | 12902461 | 2003 | Pubchem Assay |
| PRRID_0192 | Advillin Click for more detail | Host (Endogenous) (others) | MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF | 819 | Protein | Natural | It induces neurite-like outgrowth. | Scavenger receptor expressed by endothelial cells 1 (SREC-I) | Scavenger receptor (SR) | Mice (Murine) | Fibroblastic L cells | Cytoplasmic domain | Q5ND28.fasta | Q5ND28 | 820 | SREC-I lead to changes in cell morphology. | NA | 15247299 | 2004 | Pubchem Assay |
| PRRID_0192 | Advillin Click for more detail | Host (Endogenous) (others) | MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF | 819 | Protein | Natural | It induces neurite-like outgrowth. | Scavenger receptor expressed by endothelial cells 1 (SREC-I) | Scavenger receptor (SR) | Mice (Murine) | Fibroblastic L cells | Cytoplasmic domain | Q5ND28.fasta | Q5ND28 | 820 | SREC-I lead to changes in cell morphology. | NA | 15247299 | 2004 | Pubchem Assay |
| PRRID_0193 | calreticulin Click for more detail | Host (Endogenous) (others) | MLLSVPLLLGLLGLAAAEPAVYFKEQFLDGDDWTNRWVESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGSLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKASEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDEDDRDEDEEDEDEKEEDEEDTTPGQTKDEL | 417 | Protein | Natural | NA | SREC-I | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | mediates the endocytosis of calreticulin and gp96 | NA | 15371419 | 2004 | NA |
| PRRID_0193 | calreticulin Click for more detail | Host (Endogenous) (others) | MLLSVPLLLGLLGLAAAEPAVYFKEQFLDGDDWTNRWVESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGSLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKASEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDEDDRDEDEEDEDEKEEDEEDTTPGQTKDEL | 417 | Protein | Natural | NA | SREC-I | Scavenger receptor (SR) | Chinese Hamster | ovary cells | NA | NA | NA | NA | mediates the endocytosis of calreticulin and gp96 | NA | 15371419 | 2004 | NA |