Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_0094 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0094 |
| Ligand Name | Silica |
| Source | Environment particle (others) |
| Sequence of ligand | O=[Si]=O |
| Length | NA |
| Type | Chemical Compunds |
| Occurence | Natural |
| Role of Ligand | Silica particulates bind to the scavenger receptor and initiate apoptosis |
| Name of receptor | Scavenger receptor A II |
| Type of receptor | Scavenger receptor (SR) |
| Source | Chinese Hamster |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis. |
| Assay used | ELISA |
| PMID | 10637133 |
| Year of Publication | 2000 |
| Pubchem assay | NA |
| Primary information | |
|---|---|
| PRRID | PRRID_0094 |
| Ligand Name | Silica |
| Source | Environment particle (others) |
| Sequence of ligand | O=[Si]=O |
| Length | NA |
| Type | Chemical Compunds |
| Occurence | Natural |
| Role of Ligand | Silica particulates bind to the scavenger receptor and initiate apoptosis |
| Name of receptor | Scavenger receptor A II |
| Type of receptor | Scavenger receptor (SR) |
| Source | Chinese Hamster |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis. |
| Assay used | ELISA |
| PMID | 10637133 |
| Year of Publication | 2000 |
| Pubchem assay | NA |