Detailed description page of PRRDB2.0
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PRRID_0016 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0016 |
| Ligand Name | Phorbol myristate acetate (PMA) |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C |
| Length | NA |
| Type | Carbohydrate |
| Occurence | Natural |
| Role of Ligand | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | Macrophage cell line (RAW264) |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It leads to polyanion-induced macrophage plasminogen activation. |
| Assay used | Functional assay for plasmin |
| PMID | 1658006 |
| Year of Publication | 1991 |
| Pubchem assay | NA |
| Primary information | |
|---|---|
| PRRID | PRRID_0016 |
| Ligand Name | Phorbol myristate acetate (PMA) |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C |
| Length | NA |
| Type | Carbohydrate |
| Occurence | Natural |
| Role of Ligand | It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner. |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | Macrophage cell line (RAW264) |
| Localization | Macrophages |
| Domain | NA |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It leads to polyanion-induced macrophage plasminogen activation. |
| Assay used | Functional assay for plasmin |
| PMID | 1658006 |
| Year of Publication | 1991 |
| Pubchem assay | NA |