| Primary information |
|---|
| PRRID | PRRID_0168 |
| Ligand Name | gp96 (GRP94) |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL |
| Length | 803 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | C57/BL6 mice |
| Localization | macrophages and dendritic cells |
| Domain | NA |
| Sequence of Receptor | Q08857.fasta |
| Swiss prot ID | Q08857 |
| Length Of Receptor | 472 |
| Function | serves a primary role in gp96 and calreticulin recognition and internalization |
| Assay used | NA |
| PMID | 14609958 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0168 |
| Ligand Name | gp96 (GRP94) |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL |
| Length | 803 |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC |
| Name of receptor | Scavenger receptor class A |
| Type of receptor | Scavenger receptor (SR) |
| Source | C57/BL6 mice |
| Localization | macrophages and dendritic cells |
| Domain | NA |
| Sequence of Receptor | Q08857.fasta |
| Swiss prot ID | Q08857 |
| Length Of Receptor | 472 |
| Function | serves a primary role in gp96 and calreticulin recognition and internalization |
| Assay used | NA |
| PMID | 14609958 |
| Year of Publication | 2003 |
| Pubchem assay | Pubchem Assay |