Detailed description page of PRRDB2.0

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PRRID_0019 details
Primary information
PRRIDPRRID_0019
Ligand NameAsbestos
SourceCrocidolite(others)
Sequence of ligandO.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]
LengthNA
TypeSilicate Mineral
OccurenceNatural
Role of LigandCrocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.
Name of receptorScavenger receptor A I (SR-A I)
Type of receptorScavenger receptor (SR)
Source Chinese Hamster
Localizationovary cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt mediates the physiological and pathological interactions of the particles with alveolar macrophages.
Assay usedSolid-phase bead-binding assay
PMID8381434
Year of Publication1992
Pubchem assayNA
Primary information
PRRIDPRRID_0019
Ligand NameAsbestos
SourceCrocidolite(others)
Sequence of ligandO.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]
LengthNA
TypeSilicate Mineral
OccurenceNatural
Role of LigandCrocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.
Name of receptorScavenger receptor A I (SR-A I)
Type of receptorScavenger receptor (SR)
Source Chinese Hamster
Localizationovary cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt mediates the physiological and pathological interactions of the particles with alveolar macrophages.
Assay usedSolid-phase bead-binding assay
PMID8381434
Year of Publication1992
Pubchem assayNA