Detailed description page of PRRDB2.0

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PRRID_0070 details
Primary information
PRRIDPRRID_0070
Ligand NameMinimally oxidized LDL (MM-LDL)
SourceHost (Endogenous) (others)
Sequence of ligandCC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1
LengthNA
TypeLipoprotein
OccurenceNatural
Role of LigandMM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin.
Name of receptorMicrosialin
Type of receptorScavenger receptor (SR)
Source Mice
LocalizationPeritoneal macrophages
DomainNA
Sequence of ReceptorA0A0R4J1C8.fasta
Swiss prot IDA0A0R4J1C8
Length Of Receptor335
FunctionIt leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.
Assay usedEndocytic degradation assays
PMID9598839
Year of Publication1998
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0070
Ligand NameMinimally oxidized LDL (MM-LDL)
SourceHost (Endogenous) (others)
Sequence of ligandCC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1
LengthNA
TypeLipoprotein
OccurenceNatural
Role of LigandMM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin.
Name of receptorMicrosialin
Type of receptorScavenger receptor (SR)
Source Mice
LocalizationPeritoneal macrophages
DomainNA
Sequence of ReceptorA0A0R4J1C8.fasta
Swiss prot IDA0A0R4J1C8
Length Of Receptor335
FunctionIt leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.
Assay usedEndocytic degradation assays
PMID9598839
Year of Publication1998
Pubchem assayPubchem Assay