Genomic information of Breast Cancer Cell lines



This page is designed to facilitate user to browse on cell lines, it provides information related to expression, mutation and presence of genes reported to be involved in Herceptin resistance assays and mutational data as a whole. This comprehensive information about different cell lines provided on this page were collected from CCLE studies. Drug resistance profile for cell lines were obtained from CancerDR (See URL for detail). For more information, please see Guide/Help



@ Overexpressed Genes: Number of genes having expression more than 12 on scale of 0-15 in CCLE database.
@@ Underexpressed Genes: Number of genes having expressionless than 3 on scale of 0-15 in CCLE database.
* Number of genes mutated in cell line.
** Number of important genes whoese mutation cause Herceptin resistance (as per literature)
# Drug Sensitivity profile [IC50 in uM] of different breast cancer cell lines.

Result Reset Search:
Serial No. Cell line Overexpressed @ Underexpressed@@ Genes mutated* Imp. genes ** Drug Sensitivity Plot [IC50 uM]# Link to CancerDR
1 AU565 284 8231 66 1 AU565_CancerDR
2 BT474 266 7819 103 4 BT474_CancerDR
3 BT483 248 7962 42 3 Not Available BT483_CancerDR
4 BT549 277 8354 39 0 BT549_CancerDR
5 CAL51 237 7984 74 3 CAL51_CancerDR
6 CAMA1 245 8486 46 3 CAMA1_CancerDR
7 EFM192A 295 8098 26 3 Not Available EFM192A_CancerDR
8 HCC1419 279 8085 36 2 HCC1419_CancerDR
9 HCC1569 284 8211 137 4 HCC1569_CancerDR
10 HCC1937 280 7556 0 0 Not Available HCC1937_CancerDR
11 HCC1954 289 8290 54 2 HCC1954_CancerDR
12 HCC202 274 8163 54 3 Not Available HCC202_CancerDR
13 HCC70 275 7960 34 4 HCC70_CancerDR
14 HS578T 265 8111 36 2 HS578T_CancerDR
15 JIMT1 291 7643 27 3 Not Available JIMT1_CancerDR
16 KPL4 NA NA 0 0 Not Available KPL4_CancerDR
17 MCF7 292 8306 20 2 MCF7_CancerDR
18 MCF7CA NA NA 0 0 Not Available MCF7CA_CancerDR
19 MDAMB231 278 8119 49 1 MDAMB231_CancerDR
20 MDAMB361 273 7380 86 4 MDAMB361_CancerDR
21 MDAMB415 257 7988 61 4 MDAMB415_CancerDR
22 MDAMB435S NA NA 0 0 Not Available MDAMB435S_CancerDR
23 MDAMB453 283 7983 69 3 MDAMB453_CancerDR
24 MDAMB468 283 7744 46 1 MDAMB468_CancerDR
25 SKBR3 278 8124 56 1 SKBR3_CancerDR
26 T47D 249 8132 27 3 T47D_CancerDR
27 UACC732 NA NA 0 0 Not Available UACC732_CancerDR
28 UACC812 209 7708 51 1 UACC812_CancerDR
29 UACC893 281 8187 35 3 UACC893_CancerDR
30 ZR751 286 8186 11 2 ZR751_CancerDR
31 ZR7530 278 8260 53 2 ZR7530_CancerDR