HerceptinR: Herceptin Resistance Database HerceptinR

Align selected target sequences



This module allows users to perform multiple sequence alignment of selected sequences of a drug target. This option also allows users to align their own sequence against selected sequence of a drug target. Cell lines in red color are resistant, cell lines in green color are sensitive and for cell lines in black color, the assay data is not available. Click blue button to view gene sequence alignment and red for protein alignment. For more information click HERE.





 Paste your sequence, which you want to align with the mutants (in fasta format).    

  



  OR    

  Upload Sequence  

  

Select PIK3CA Mutants



  BT20(c.1616C>G,c.3140A>G)
  BT474(c.333G>C)
  BT483(c.1624G>A)
  CAL148(c.1048G>A,c.3140A>G)
  CAL51(c.1624G>A)
  EFM192A(c.1258T>C)
  EFM19(c.3140A>T)
  HCC1954(c.3140A>G)
  HCC202(c.1633G>A,c.2598G>C)
  HCC38(c.1157G>T)
  JIMT1(c.1258T>C)
  KPL1(c.1633G>A)
  MCF7(c.1633G>A)
  MDAMB361(c.1633G>A,c.1700A>G)
  MDAMB453(c.3140A>G)
  T47D(c.3140A>G)
  UACC893(c.3140A>G)
  Check All


 


Select any one of the Targets
BRCA2 MAP3K1 PIK3CA PTEN RB1 TP53