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The total number entries retrieved from this search are 378| Biomarker ID | Biomarker | Biomolecule | Subject | Regulation | Biomarker's type | Experiment | Level of significance | Source | PMID |
|---|---|---|---|---|---|---|---|---|---|
| 2482 | COMT | Protein | Human | Downregulated in HCC tissues in HCC tumor than non-tumor | Diagnostic | HCC v/s non-tumor | p < 0.01 | Tissue | 17627933 |
| 2483 | MYO1D, EST, PDGF-B, LOC113246, SPTAN1, MGC19556, IL6R, PRPSAP1, PDCD6IP, AHNAK, BCL2L11, GPAA1, c-fos, SLC11A2, LOC51235, PRPF8, CD36L1, KIAA1055, HNRPDL, NDRG1, NARS, PABPC4, RDBP, CALM2, PDCD6, C1R, ALB, MT1G, CED-6, AMACR, A2M, FGG, SUPV3L1, PHLDA1, NBP, HAMP, HCS, KIAA0635, ECHS1, SHMT1, NNMT, A | RNAs | Human | Differentially expressed between HCC and non-tumor liver tissue | Diagnostic | HCC v/s non-tumor | p < 0.01 | Tissue | 14642619 |
| 2484 | SOX6, ITIH4, HDGF, SKIP1, RBP4, LOC92033, UGT2B7, FABP1, GATM, UQCRC1, UK114, CP, PBEF, KAL1, CES2, GPX4, UGT1A4, RCL, PABPC1, EST, FGA, RARRES2, SLC22A, SRP14, FLJ14294, cyclin, CA2, CLDN1, FTL, FLJ10004, CYP3A5, ARHGEF12, TDO2, NDUFB2, TEGT, SPR, PCK2, MGC13114, EST, MTHFS, F2, FLJ22313, C9orf5, H | RNAs | Human | Differentially expressed between HCC and normal tissues | Diagnostic | HCC v/s normal | p < 0.01 | Tissue | 14642619 |
| 2485 | IGFBP3, c-fos, p21 | RNAs | Human | Differentially expressed between HCC and non-tumor liver tissue | Diagnostic | HCC v/s non-tumor | p < 0.01 | Tissue | 14642619 |
| 2486 | p53, cyclin D1 | RNAs | Human | Differentially expressed between HCC and normal tissues | Diagnostic | HCC v/s normal | p < 0.01 | Tissue | 14642619 |
| 2487 | Protein disulfide isomerase A3 | Protein | Human | Upregulated in HCC than non tumor (with mean ratio of 4.3 +/- 3.7) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2488 | Heat shock 27 kDa protein | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 8.4 +/- 5.8) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2489 | Glycerol-3-phosphate dehydrogenase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 9.9 +/- 9.6) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2490 | Senescence marker protein-30 | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 7.9 +/- 11.1) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2491 | Acyl-CoA dehydrogenase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 4.7 +/- 2.5) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2492 | Ketohexokinase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 4.7 +/- 3.7) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2493 | GRB2 | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 6.7 +/- 5.4) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2494 | Aldehyde dehydrogenase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 3.7 +/- 2.8) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2495 | Cathepsin D | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 3.5 +/- 3.3) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2496 | Guanidinoacetate N-methyltransferase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 5.3 +/- 8.6) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2497 | Catechol O-methyltransferase | Protein | Human | Downregulated in HCC than non tumor (with mean ratio of nearly 3.2 +/- 3.8) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 12481271 |
| 2498 | TGM2 | Protein | Human | Upregulated in HCC than non tumor | Diagnostic | HCC v/s normal | p < 0.05 | Cell line, Tissue, Serum | 18646787 |
| 2500 | RYBP, ATP1B3, TMC, ZNF567, GPR108, CD19, SPINK1, CDC2L6, RSRC1, METAP, GPC3, SNHG11, RY1, CRELD2, GLUL, SERPINB1, TRMT6, UNC13D, E4F1--E4F, SLC22A2, CNIH4, TK1, MAFB, PPP1CB, DNTTIP2, ARID4B, SMARCC2, PRO1386, TRIOBP, VARS, ITGA5, TERF1, PURA, TUBA1B, SNRPE, RRAGD, VWF, GLRX3, ILF2, | RNAs | Human | Upregulated in HCV related HCC than normal control (With 3-fold change) | Diagnostic | HCV related HCC v/s normal control | p < 0.01 | Tissue | 19821982 |
| 2501 | NMNAT3, OASL, TMPRSS3, MFSD7, AEBP1, UBD, S100A4, C1orf151, CRIP1, ASCC3, ZNF271, ANXA4, NMI, UBE2L6, B2 M, HLA-F, PSMB9, TAP1, PSME2, IFI16, IFI27, ARHGAP9, RABGAP1L, TNK1, DEF6, BTN3A3, RPS6KA1, CD24, PARP10, APOL3, STAT, ANKRD10, CKB, H2AFZ, PSMB9, RARRES3, RGS10, TUBB, NOL3, CD7, | RNAs | Human | Upregulated in HCV related non-HCC than normal control (With 3-fold change) | Diagnostic | HCV related non-HCC v/s normal control | p < 0.01 | Tissue | 19821982 |
| 2502 | CAPG, OCC-1, EED, RPLP0, RPLP0P2, AP1S2, RRAGD, PFDN4, CCDC104, C7orf28B, PSIP1, LPCAT1, FSCN3, RAB24, ZNF446, SEC11B, ZNF586, SCNM1, SF3A1, RUFY1, TRIM55, GOLGA4, GPATCH4, THOP1, TUBB2C, PHLDB3, FAM104A, FASTK, EIF2AK4, ZFP41, PRKRIP1, DSTN, PHIP, NUCKS1, TNRC8, CCDC132, EPRS, HIST1H4C, CDCA8, | RNAs | Human | Upregulated in HCV related HCC than HCV related non-HCC (With 3-fold change) | Diagnostic | HCV related HCC v/s HCV related non-HCC | p < 0.01 | Tissue | 19821982 |
| 2503 | Fibronectin, Tubulin-alpha-1 subunit, Matrix metalloproteinase 14, osteonectin SPARC, RAD23A, Ubiquitin-conjugating enzyme E2, Neutrophil-gelatinase associated lipocalin precursor lipocalin 2, TRAM protein, ADP/ATP carrier protein, High mobility group protein, Insulin stimulated protein kinase 1, Tr | RNAs | Human | Diffrenetially expressed in HCC v/s non-tumor | Diagnostic | HCC v/s non-tumor | p < 0.01 | Tissue | 11973655 |
| 2504 | CDC28 protein kinase2, CDC27HS protein, Integrin beta 4, Desmoplakin 1/2, Procollagen C proteinase, platelet derived growth factor, cytidine deaminase, aminoacyalse1, Betaine homocysteine S-methyltransferase, methylenetetrahydrofolate dehydrogease, metalloproteinase inhibitor1, aldehyde oxidase, met | RNAs | Human | Diffrenetially expressed in HCV and HBV associated HCC v/s non-tumor | Diagnostic | HCV and HBV associated HCC v/s non-tumor | p < 0.01 | Tissue | 11973655 |
| 2505 | Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated protei | RNAs | Human | Diffrenetially expressed in cirrhotic v/s non-cirrhotic | Diagnostic | cirrhotic v/s non-cirrhotic | p < 0.01 | Tissue | 11973655 |
| 2506 | Zinc finger protein, integrin alpha 6, hepatoma derived growth factor, TGF beta induced, Macrophage inhibitory cytokine 1, lymphocyte antigen, aldehyde oxidase, c-myc purine binding transcription factor puf, plasminogen, vitronectin, hemoglobin alpha subunit, cytosolic superoxide dismutase, methylen | RNAs | Human | Diffrenetially expressed in moderately differentiated HCC v/s poorly differentiated HCC | Diagnostic | moderately differentiated HCC v/s poorly differentiated HCC | p < 0.01 | Tissue | 11973655 |
| 2507 | SGCE | RNAs | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 19171046 |
| 2508 | PEG10 | RNAs | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 19171046 |
| 2509 | CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1 | RNAs | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 19171046 |
| 2510 | FGL2 | Protein | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2511 | MYADM | Protein | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2512 | GC | Protein | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2513 | OTC | Protein | Human | Downregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2514 | FGL2, GC, FLNA, FHL1, FBN2, TLN1 | Protein | Human | Upregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2515 | OTC, PEBP1, FABP1, CPS1, ARG1, EPHX1 | Protein | Human | Downregulated in HCC than non-tumor (with > 3 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 18715028 |
| 2516 | MT1G | Protein | Human | Downregulated in HCC than non-tumor (with 100 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.001 | Tissue | 16980951 |
| 2517 | FGG | Protein | Human | Downregulated in HCC than non-tumor (with 100 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 16980951 |
| 2518 | FGL1 | Protein | Human | Downregulated in HCC than non-tumor (with 100 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 16980951 |
| 2519 | Alpha-2-plasmin inhibitor, SERPINF2 | Protein | Human | Downregulated in HCC than non-tumor (with 100 fold change) | Diagnostic | HCC v/s non-tumor | p < 0.05 | Cell line, Tissue | 16980951 |
| 2522 | BIC, CPNE1, RBPMS, RFC4, RPSA, TOP2A | RNAs | Human | Upregulated in dedifferentiated HCC (with fold change > 2.6) | Diagnostic | moderately and well differentiated HCC v/s low-differentiated HCC | FDR < 2%. | Tissue | 18820673 |
| 2523 | MT1G, MT1F | RNAs | Human | Downregulated in dedifferentiated HCC (with fold change of > 0.35) | Diagnostic | moderately and well differentiated HCC v/s low-differentiated HCC | FDR < 5%. | Tissue | 18820673 |
| 2525 | Cytoplasmic dynein light chain, Hepatoma-derived growth factor, Ribosomal protein L6, glutathioneS-transferase, Fibronectin, Ras homolog gene family member B, TR3 orphan receptor, c-myc transcription factor (puf), MHC-class IC | RNAs | Human | Upregulated in HCC than non-tumorous tissue ( with average ratio more than 2) | Diagnostic | HCC v/s non-tumor | NA | Tissue | 11283847 |
| 2526 | Plasminogen, Corticotropin releasing hormone bindingprotein, GRO2 oncogene, Interferon gamma-inducible protein 10, alpha-Platelet-derived growth factor receptor precursor, Cell division cycle 25C, Cytochrome P450-IIC, Human intercrine-a(hIRH), IL-8 | RNAs | Human | Downregulated in HCC than non-tumorous tissue ( with average ratio more than 2) | Diagnostic | HCC v/s non-tumor | NA | Tissue | 11283847 |
| 2527 | transgelin 2 | RNAs | Human | Upregulated in HCC than non-tumorous tissue | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 15756260 |
| 2528 | B-factor | RNAs | Human | Downregulated in HCC than non-tumorous tissue | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 15756260 |
| 2529 | HDAC2, PSMA7, PSMD1 | RNAs | Human | Upregulated in HCC than non-tumorous tissue | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 15756260 |
| 2530 | HIMAP4, C5 | RNAs | Human | Downregulated in HCC than non-tumorous tissue | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 15756260 |
| 2531 | TRIM25, EIF2S3, CLECSF14, DXYS155E, T-cell receptor beta locus, GIF2H2, SPON2, VDAC2, SLC15A3, HBP1, PTPRC, FES, CDC5L, ITGB2, MPP1, NDUFA2, AHCYL1, CNP, SQLE, RPA3, LGALS1, HLA-DQA1 , STMN1, PCOLCE, LOC387680, DPT, SLK, IGBP1, SNRPG, Human-alpha1-antitrypsin gene (S variant) complete cds, SIAHBP1, | RNAs | Human | 7 genes Downregulated i.e. CYP1A2, Human-alpha1-antitrypsin gene (S variant) complete cds, PCOLCE, CNP, DXYS155E, CLECSF14, TRIM25 and 29 get upregulated in | Diagnostic and prognostic | Single nodular HCC group v/s multicentric HCC group; associated with multicentric recurrence | p < 0.05 | Tissue | 16788756 |
| 2532 | GPC3, NCSTN, LCN2, PLK, PSK-1, PTTG1 | RNAs | Human | Upregulated in HCC than non-tumorous tissue | Diagnostic | HCC v/s non-tumor | p < 0.05 | Tissue | 15735714 |
| 2533 | PTMA | RNAs | Human | Upregulated in mt-p53 HCC than wt-p53 HCC and non-cancerous tissue (with Fisher ratios of >2.12) | Diagnostic | mutant-p53 HCC v/s wild type-p53 HCC and non-cancerous tissue | p < 0.01 | Tissue | 14675778 |
| 2534 | NUMA1 | RNAs | Human | Downregulated in mt-p53 HCC than wt-p53 HCC ; Upregulated in wt-p53 HCC than of non-cancerous liver (with Fisher ratios of >2.12) | Diagnostic | mutant-p53 HCC v/s wild type-p53 HCC and non-cancerous tissue | p < 0.01 | Tissue | 14675778 |
| 2538 | ILF2, BMI1, TAF9, RFX5, SSRP1, ZNF146, SREBF2, MAFG, CHD4, NR4A1, ESR1, ZNF238, FOSB, ID1, FOS, H2AFY, SNRPB, RPS7, MRPS14, HNRPU, SNRPD2, NCL, RPS10, RPL6, SFPQ, DIM1, MARS, SFRS9, RBM3, U2AF65, SFRS1, SNRPE, SF3B4, RDBP, SNRPF, RRM1, RPL38, HNRPH1, U5-116KD, RPLP1, OXA1L, ADPRT, PRKDC, SMC4L1, H2A | RNAs | Human | Differentially Expressed in HCC Tumors than non-tumor (with fold change of 1.5) | Diagnostic | HCC v/s non-tumor | p < 0.01 | Tissue | 15057898 |