CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2509
Detailed information
CancerLivER ID2509
Biomarker CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1
Biomarker Name/Symbol (given in Publication)CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1
BiomoleculeRNAs
SubjectHuman
Degree of ValiditySignificantly Upregulated in HCC than non-tumor and validated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC than non-tumor (with > 3 fold change)
Level of significance p < 0.05
SourceCell line, Tissue
PMID19171046
Type of BiomarkerDiagnostic
PathwayInterleukin-10 signaling and TNF signaling pathway, Validated target for C-MYC transcriptional activation.
CohortTraining dataset: HCC cell line HepG2 , Normal liver tissue was obtained from a patient, Validation datasets: 20 pairs of HCC and adjacent nontumorous liver tissues;
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s non-tumor
Year of Publication2009
Clinical trialNO
Clinical trial (NCT Number)NA

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