Detailed information |
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CancerLivER ID | 2509 |
Biomarker | CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1 |
Biomarker Name/Symbol (given in Publication) | CCL20, S100P, PEG10, SGCE, XAGE-1, COL4A1, ZNF83, and TM4SF1 |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Significantly Upregulated in HCC than non-tumor and validated on independent dataset |
Experimental Condition | HCC v/s non-tumor |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC than non-tumor (with > 3 fold change) |
Level of significance | p < 0.05 |
Source | Cell line, Tissue |
PMID | 19171046 |
Type of Biomarker | Diagnostic |
Pathway | Interleukin-10 signaling and TNF signaling pathway, Validated target for C-MYC transcriptional activation. |
Cohort | Training dataset: HCC cell line HepG2 , Normal liver tissue was obtained from a patient, Validation datasets: 20 pairs of HCC and adjacent nontumorous liver tissues; |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC v/s non-tumor |
Year of Publication | 2009 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |