| Detailed information |
|---|
| CancerLivER ID | 2506 |
| Biomarker | Zinc finger protein, integrin alpha 6, hepatoma derived growth factor, TGF beta induced, Macrophage inhibitory cytokine 1, lymphocyte antigen, aldehyde oxidase, c-myc purine binding transcription factor puf, plasminogen, vitronectin, hemoglobin alpha subunit, cytosolic superoxide dismutase, methylen |
| Biomarker Name/Symbol (given in Publication) | Zinc finger protein, integrin alpha 6, hepatoma derived growth factor, TGF beta induced, Macrophage inhibitory cytokine 1, lymphocyte antigen, aldehyde oxidase, c-myc purine binding transcription factor puf, plasminogen, vitronectin, hemoglobin alpha subunit, cytosolic superoxide dismutase, methylenetetrahydrofolate dehydrogease, Dihydro-orotate dehydrogenas |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Potential diagnostic marker for HCC and diffrenetially expressed in moderately differentiated HCC v/s poorly differentiated HCC; but not validated on independent dataset |
| Experimental Condition | moderately differentiated HCC v/s poorly differentiated HCC |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Diffrenetially expressed in moderately differentiated HCC v/s poorly differentiated HCC |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 11973655 |
| Type of Biomarker | Diagnostic |
| Pathway | Metabolic pathways, growth factor, regulate immune response, cell cycle, cytoskelton |
| Cohort | 15 HCC patients: 8 HCV positive-HCC, 6 HBV-positive HCC and one HCV and HBV associated HCC. Histological analysis of non-tumour tissues showed that 11 HCCs had developed on cirrhotic and 4 on non-cirrhotic tissues; 5 well differentiated HCCs, and 10 moderately or poorly differentiated HCC. |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | moderately differentiated HCC v/s poorly differentiated HCC |
| Year of Publication | 2002 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |