CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2486
Detailed information
CancerLivER ID2486
Biomarker p53, cyclin D1
Biomarker Name/Symbol (given in Publication)p53 and cyclin D1
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential Diagnostic marker for HCC and validated on independent dataset
Experimental ConditionHCC v/s normal
Cancer typeHepatocellular carcinoma
RegulationDifferentially expressed between HCC and normal tissues
Level of significance p < 0.01
SourceTissue
PMID14642619
Type of BiomarkerDiagnostic
PathwayCell cycle and apoptosis
CohortTraining dataset: 68 non-B, non-C liver samples, including 20 T and 17 NT samples, that were obtained from non-B, non-C HCC patients, and 31 N samples from metastatic liver cancer patients; Validation dataset: 37 non-B, non-C liver tissues (20 HCC, 17 non-tumor liver) from 20 patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s normal
Year of Publication2003
Clinical trialNO
Clinical trial (NCT Number)NA

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