CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2497
Detailed information
CancerLivER ID2497
Biomarker Catechol O-methyltransferase
Biomarker Name/Symbol (given in Publication)Catechol O-methyltransferase, membrane-bound form
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential biomarker for HCC or differentially expressed between HCC and non-tumor liver tissue; but not validated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC than non tumor (with mean ratio of nearly 3.2 +/- 3.8)
Level of significance p < 0.05
SourceTissue
PMID12481271
Type of BiomarkerDiagnostic
PathwayCytochrome P450 - arranged by substrate type and Dopamine metabolism
CohortPaired tumor and nontumor tissues from 11 HCC patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s non-tumor
Year of Publication2002
Clinical trialNO
Clinical trial (NCT Number)NA

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