Biomarker ID 2504 |
| Detailed information | |
|---|---|
| CancerLivER ID | 2504 |
| Biomarker | CDC28 protein kinase2, CDC27HS protein, Integrin beta 4, Desmoplakin 1/2, Procollagen C proteinase, platelet derived growth factor, cytidine deaminase, aminoacyalse1, Betaine homocysteine S-methyltransferase, methylenetetrahydrofolate dehydrogease, metalloproteinase inhibitor1, aldehyde oxidase, met |
| Biomarker Name/Symbol (given in Publication) | CDC28 protein kinase2, CDC27HS protein, Integrin beta 4, Desmoplakin 1/2, Procollagen C proteinase, platelet derived growth factor, cytidine deaminase, aminoacyalse1, Betaine homocysteine S-methyltransferase, methylenetetrahydrofolate dehydrogease, metalloproteinase inhibitor1, aldehyde oxidase, metalothionein-III, Dihydro-orotate dehydrogenase, STAT-induced STAT inhibitor 2, STAT-induced STAT inhibitor 3, Insulin induced protein 1, hemoglobin alpha subunit, Gravin, EGF response factor 1, EGF receptor ERBB1, Growth factor receptor bound protein 2 isoform, hepatocyte growth factor activator, DNAX activation protein 12, STAT3, Leukocyte IgG receptor, IL-1 receptor antagonist precursor, Polyhomeotic 2 homologue, KIAA0022, cyclin dependent kinase inhibitor1 p21, guanine nucleotide binding protein G, PIG7, TGF beta induced, MHC enhancer binding protein MAD3, FC-epsilon receptor gamma subunit, HLA-DR antigen associated invariant subunit, cytidine deaminase |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Potential diagnostic marker for HCC and diffrenetially expressed in HCV and HBV associated HCC v/s non-tumor; but not validated on independent dataset |
| Experimental Condition | HCV and HBV associated HCC v/s non-tumor |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Diffrenetially expressed in HCV and HBV associated HCC v/s non-tumor |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 11973655 |
| Type of Biomarker | Diagnostic |
| Pathway | Metabolic pathways, growth factor, regulate immune response, cell cycle |
| Cohort | 15 HCC patients: 8 HCV positive-HCC, 6 HBV-positive HCC and one HCV and HBV associated HCC. Histological analysis of non-tumour tissues showed that 11 HCCs had developed on cirrhotic and 4 on non-cirrhotic tissues; 5 well differentiated HCCs, and 10 moderately or poorly differentiated HCC. |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | HCV and HBV associated HCC v/s non-tumor |
| Year of Publication | 2002 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |