Detailed information |
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CancerLivER ID | 2515 |
Biomarker | OTC, PEBP1, FABP1, CPS1, ARG1, EPHX1 |
Biomarker Name/Symbol (given in Publication) | OTC, PEBP1, FABP1, CPS1, ARG1 and EPHX1 |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Potential diagnostic marker for HCC and downregulated in HCC than non-tumor (with > 3 fold change); but not validated on independent dataset |
Experimental Condition | HCC v/s non-tumor |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HCC than non-tumor (with > 3 fold change) |
Level of significance | p < 0.05 |
Source | Tissue |
PMID | 18715028 |
Type of Biomarker | Diagnostic |
Pathway | amino acids metabolic pathway |
Cohort | 56 HCC: 13 metastatic tissues along with 46 poor to well differentiated hepatocellular carcinoma from patients in the age group of 40 to 72 years and 59 noncancer tissues; The tissue microarrays from Creative Biolabs consisted of 15 well differentiated, 29 moderately differentiated, and 12 poorly di |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC v/s non-tumor |
Year of Publication | 2008 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |