Detailed information |
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CancerLivER ID | 2523 |
Biomarker | MT1G, MT1F |
Biomarker Name/Symbol (given in Publication) | MT1G, and MT1F |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Markers to distinguish diffrenetiated and dedifferentiated HCC; but not validated on independent dataset |
Experimental Condition | moderately and well differentiated HCC v/s low-differentiated HCC |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in dedifferentiated HCC (with fold change of > 0.35) |
Level of significance | FDR < 5%. |
Source | Tissue |
PMID | 18820673 |
Type of Biomarker | Diagnostic |
Pathway | Metallothioneins bind metals and Metal ion SLC transporters. |
Cohort | 23 HCC patients: 4 well, 11 moderately, and 8 poorly differentiated HCC |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | moderately and well differentiated HCC v/s low-differentiated HCC |
Year of Publication | 2008 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |