Detailed information |
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CancerLivER ID | 2516 |
Biomarker | MT1G |
Biomarker Name/Symbol (given in Publication) | Metallothionein 1G, MT1G |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Potential candidate gene for deletion hotspots of hepatocellular carcinoma |
Experimental Condition | HCC v/s non-tumor |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated in HCC than non-tumor (with 100 fold change) |
Level of significance | p < 0.001 |
Source | Tissue |
PMID | 16980951 |
Type of Biomarker | Diagnostic |
Pathway | Metallothioneins bind metals and Metal ion SLC transporters |
Cohort | Tumorous liver tissue was collected from 38 patients and adjacent nonmalignant liver tissue was secured for 30 patients; one case was graded as stage I, 20 cases as stage II, 11 as stage III and six as stage IV; Microarray analysis was conducted on 20 HCCs, of which retrievable tumor RNA from 12 cas |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | HCC v/s non-tumor |
Year of Publication | 2006 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |