CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2516
Detailed information
CancerLivER ID2516
Biomarker MT1G
Biomarker Name/Symbol (given in Publication)Metallothionein 1G, MT1G
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential candidate gene for deletion hotspots of hepatocellular carcinoma
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC than non-tumor (with 100 fold change)
Level of significance p < 0.001
SourceTissue
PMID16980951
Type of BiomarkerDiagnostic
PathwayMetallothioneins bind metals and Metal ion SLC transporters
CohortTumorous liver tissue was collected from 38 patients and adjacent nonmalignant liver tissue was secured for 30 patients; one case was graded as stage I, 20 cases as stage II, 11 as stage III and six as stage IV; Microarray analysis was conducted on 20 HCCs, of which retrievable tumor RNA from 12 cas
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s non-tumor
Year of Publication2006
Clinical trialNO
Clinical trial (NCT Number)NA

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