| Detailed information |
|---|
| CancerLivER ID | 2505 |
| Biomarker | Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated protei |
| Biomarker Name/Symbol (given in Publication) | Lactate dehydrogenase, aldehyde oxidase, nucleoside diphosphate kinase, alpha 1 catenin, beta catenin, transforming protein rho B, IgG, IgGK, IgG3, IgG1, IgG1K, IgA1, IgHA, IgG1-Fc, Collagen - alpha 1 subunit, c-jun N-terminal kinase 2, ADP/ATP carrier protein, Progression receptor associated protein, type 2 cytoskeletal 8 keratin, Growth factor receptor bound protein 2/3, PKC inhibitor 1, IL-1 receptor antagonist precursor, FC-epsilon receptor gamma subunit, guanine nucleotide binding protein G, Rho-GTPase activation protein 4 |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Potential diagnostic marker for HCC and diffrenetially in cirrhotic v/s non-cirrhotic; but not validated on independent dataset |
| Experimental Condition | cirrhotic v/s non-cirrhotic |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Diffrenetially expressed in cirrhotic v/s non-cirrhotic |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 11973655 |
| Type of Biomarker | Diagnostic |
| Pathway | Metabolic pathways, growth factor, regulate immune response, cell cycle, cytoskelton |
| Cohort | 15 HCC patients: 8 HCV positive-HCC, 6 HBV-positive HCC and one HCV and HBV associated HCC. Histological analysis of non-tumour tissues showed that 11 HCCs had developed on cirrhotic and 4 on non-cirrhotic tissues; 5 well differentiated HCCs, and 10 moderately or poorly differentiated HCC. |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | cirrhotic v/s non-cirrhotic |
| Year of Publication | 2002 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |