| Detailed information |
|---|
| CancerLivER ID | 2493 |
| Biomarker | GRB2 |
| Biomarker Name/Symbol (given in Publication) | Growth factor receptor-bound protein 2 or GRB2 |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Potential biomarker for HCC or differentially expressed between HCC and non-tumor liver tissue; but not validated on independent dataset |
| Experimental Condition | HCC v/s non-tumor |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Downregulated in HCC than non tumor (with mean ratio of nearly 6.7 +/- 5.4) |
| Level of significance | p < 0.05 |
| Source | Tissue |
| PMID | 12481271 |
| Type of Biomarker | Diagnostic |
| Pathway | Development Dopamine D2 receptor transactivation of EGFR |
| Cohort | Paired tumor and nontumor tissues from 11 HCC patients |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | HCC v/s non-tumor |
| Year of Publication | 2002 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |