| Detailed information |
|---|
| CancerLivER ID | 2519 |
| Biomarker | Alpha-2-plasmin inhibitor, SERPINF2 |
| Biomarker Name/Symbol (given in Publication) | Alpha-2-plasmin inhibitor, SERPINF2 |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Potential candidate gene for deletion hotspots of hepatocellular carcinoma. |
| Experimental Condition | HCC v/s non-tumor |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Downregulated in HCC than non-tumor (with 100 fold change) |
| Level of significance | p < 0.05 |
| Source | Cell line, Tissue |
| PMID | 16980951 |
| Type of Biomarker | Diagnostic |
| Pathway | Formation of Fibrin Clot (Clotting Cascade) and Response to elevated platelet cytosolic calcium ions |
| Cohort | Tumorous liver tissue was collected from 38 patients and adjacent nonmalignant liver tissue was secured for 30 patients; one case was graded as stage I, 20 cases as stage II, 11 as stage III and six as stage IV; Microarray analysis was conducted on 20 HCCs, of which retrievable tumor RNA from 12 cas |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | HCC v/s non-tumor |
| Year of Publication | 2006 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |