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The total number entries retrieved from this search are 378
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2400Acyl-CoA dehydrogenaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2401Fatty acid synthaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2402Adenosine deaminaseRNAsHumanUpregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2403CYP450-IIBRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2404CYP450-IICRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2405CYP450-IIC17RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2406CYP450-IIE1RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2407P450 mRNA encoding nifedipine oxidaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2408Cholesterol side chain cleavage enzyme P450RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2409Lanosterol 14-demethylase cytochrome P450RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2410Glutathione S-transferase θ1RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2411Glutathione S-transferaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2412Glutathione S-transferase M3RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2413Glutathione S-transferase θ2RNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2414Monoamine oxidase ARNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2415Chlordecone reductaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2416Dihydropteridine reductaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2417Zeta-crystallin/quinone reductaseRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2418Ubiquinol-cytochrome c reductase subunitRNAsHumanDownregulated in HCC than non-tumor DiagnosticHCC v/s non-tumor p < 0.05Tissue11752456
2419IGF2ProteinHumanUpregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2420ADAM9ProteinHumanUpregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2421STAT3ProteinHumanUpregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2422SOCS3ProteinHumanUpregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2423cyclin D1ProteinHumanUpregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2424COL1A1ProteinHumanDownregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2425SMAD4ProteinHumanDownregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2426FHITProteinHumanDownregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2427SOCS1ProteinHumanDownregulated in HCC than normal DiagnosticHCC v/s normal (R2 = 0.85) compared with HCC versus normal liver (R2 = 0.51)Tissue14517841
2429reticulon 4 or RTN4RNAsHumanDownregulated in HCC than non-tumor (with fold change of 2.8) DiagnosticHCC v/s non-tumor p < 0.05Tissue16463013
2430RGS-1RNAsHumanDownregulated in HCC than non-tumor (with fold change of 8.5) DiagnosticHCC v/s non-tumor p < 0.05Tissue16463013
2431antiplasminRNAsHumanDownregulated in HCC than non-tumor (with fold change of 3.2) DiagnosticHCC v/s non-tumor p < 0.05Tissue16463013
2432kallikrein BRNAsHumanDownregulated in HCC than non-tumor (with fold change of 10.5) DiagnosticHCC v/s non-tumor p < 0.05Tissue16463013
2461FAM34A, NARS, HSPC152, GRP58, GBA, PVRL2, RPS17, LAMR1, GNB1, AHNAK, GRCC10, SPTAN1, CTSC, NSE1, COP1, NDRG1, HSPA5, SPARC, ATP5J2, KIAA0663, CD24, NUDT3, CANXRNAsHumanDownregulated in among all types HCC v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue16391793
2462SMYD3, FABP1, Ceruloplasmin, A2M, IGFBP, PPAP2B, SHMT, PHLDA1, APOA1, SOCS2, ETS2, MT2A, CYP39A1, HAMP, CYP2C9, SLC22A1, PLG, GAMT, FGG, KRT8, IFITM1, C1R, FGB, FGA, GC (vitamin D binding protein), SERPINA3, WAC,RNAsHumanUpregulated in among all types HCC v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue16391793
2463CLURNAsHumanUpregulated in metastatic HCC than primary HCC Diagnostic and PrognosticPrimary and metastatic HCC p < 0.001Cell line and Tissue16247463
2465GPC3, CAP2, UBD, MT1F, PTDSS1, RDS, ID1, NNMT, AA127809, PRRG2, ACAA1, SLC22A1, BE779749, FACL2, PRLR, C8orf4, C6, CCNH, AK022114, CBFA2T3, EPAS1, API5, SULT2A1, PGM1, C9, NQO1, C1R, PMS1, DSCR1, PPP1R2, GOT1, ZNF6, AI831040, GCLC, MYOZ2, HMGCL, UBE4A, SERPING1, PLG, ADFP, RODH, MARCO, C9orf59, BG71RNAsHumanDifferentially expressed (GPC3, CAP2, UBD Upregulated and rest 41 are Downregulated) in tumor v/s non-tumor DiagnosticHCC v/s non-tumor p < 0.001Tissue15607117
2467GRP94, GRP78, GRP75, HSC71, HSP90, HSP70, HSP60, Aconitase, EF-2, Nucleophosmin, VIM, NDK-A, Argininosuccinate synthase, CPSASE-I,ProteinHumanDifferentially expressed (Argininosuccinate synthase, Carbamoyl-phosphate synthase (CPSASE I) are Downregulated and rest 12 are Upregulated) in HCC tumor v/s non-tumorous DiagnosticHCC tumor v/s non-tumorous p < 0.05Tissue14654528
2468hnRNP K, HSP70RY, Lamin B1, 40S ribosomal protein SA, FTCD, SOD, Arginase, SMP-30, P5C dehydrogenase, Transitional endoplasmic reticulum ATPase, Ubiquitin carboxyl-terminal hydrolase 5, Thiosulfate sulfurtransferase (Rhodanese), Betaine-himocysteine S-methyltransferase, NCC27, FGB, RACK1, PDI, SARDHProteinHumanDifferentially expressed (hnRNP K, HSP70 RY, Lamin B1, 40S ribosomal protein SA, Transitional endoplasmic reticulum ATPase, Ubiquitin carboxyl-terminal hydrolase 5, Rhodanese, Betaine-himocysteine S-methyltransferase, NCC27, Fibrinogen β chain, RACK1 are Upregulated and rest 12 are Downregulated) DiagnosticHBV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2469GABA-AT, Cytosol aminopepsidase, AFB1-AR2, Acyl-CoA dehydrogenase, GDH,ProteinHumanDifferentially expressed (GABA-AT, AFB1-AR2) are Upregulated and rest 3 are Downregulated) in HCC tumor v/s non-tumorous DiagnosticHCV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2470HSP27, Enoyl-CoA hydratase, Tubulin β chain, Galactose kinase, Ubiquinol-cytochrome C reductase complex core protein I, Annexin V, P-PST, Ribosome binding protein, Fumarylacetoacetase, ALDH, Catalase,ProteinHumanDifferentially expressed (P-PST, Ribosome binding protein, Fumarylacetoacetase, Catalase and ALDH are Downregulated and rest 6 are Upregulated) in HCC tumor v/s non-tumorous DiagnosticBoth HBV- and HCV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2471Protein disulfide isomerase ER-60, PRBP, Tropomyosin 3, ATP synthase, Dihydropipoamide dehydrogenase, FABP, Cathepsin B1,ProteinHumanDifferentially expressed (FABP, Cathepsin B1 are Downregulated and rest 5 are Upregulated) in HCC tumor v/s non-tumorous Diagnosticboth (HBV and HCV) negative HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2473hnRNP C1/C2ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2474Hcp70/Hsp90-organizing protein (HOP)ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2475GRP-78ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2476heat shock 70-kDa protein 1ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2477heat shock 70-kDa protein 4ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2478T-complex protein 1ProteinHumanUpregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2479MATProteinHumanDownregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2480GNMTProteinHumanDownregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933
2481BHMTProteinHumanDownregulated in HCC tissues in HCC tumor than non-tumor DiagnosticHCC v/s non-tumor p < 0.01Tissue17627933

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