| Detailed information |
|---|
| CancerLivER ID | 2461 |
| Biomarker | FAM34A, NARS, HSPC152, GRP58, GBA, PVRL2, RPS17, LAMR1, GNB1, AHNAK, GRCC10, SPTAN1, CTSC, NSE1, COP1, NDRG1, HSPA5, SPARC, ATP5J2, KIAA0663, CD24, NUDT3, CANX |
| Biomarker Name/Symbol (given in Publication) | FAM34A or Family with sequence similarity 34 member A (FAM34A), NARS or Asparaginyl-tRNA synthetase, HSPC152 or Hypothetical protein HSPC152, GRP58 or Glucose regulated protein 58 kDa, GBA or Glucosidase ß, PVRL2 or Poliovirus receptor-related 2, RPS17 or Ribosomal protein S17, LAMR1 or Laminin receptor 1, GNB1 or Guanine nucleotide binding protein ß polypeptide 1, AHNAK or AHNAK nucleoprotein (desmoyokin), GRCC10 or Likely ortholog of mouse gene rich cluster C10 gene, SPTAN1 or Spectrin · non-erythrocytic 1, CTSC or Cathepsin C, NSE1 or Non-SMC (structural maintenance of chromosomes) element 1 protein, COP1 or Constitutive photomorphogenic protein, NDRG1 or N-myc downstream regulated gene 1, HSPA5 or Heat shock 70 kDa protein 5, SPARC or Secreted protein acidic cysteine-rich, ATP5J2 or ATP synthase H+ transporting mitochondrial F0 complex subunit f isoform 2, KIAA0663 or KIAA0663 gene product, CD24 or CD24 antigen (small cell lung carcinoma cluster 4 antigen), NUDT3 or Nudix (nucleoside diphosphate linked moiety X)-type motif 3, CANX or Calnexin |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Potential diagnostic marker for HCC; but not validated on independent dataset |
| Experimental Condition | HCC v/s non-tumor |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Downregulated in among all types HCC v/s non-tumor |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 16391793 |
| Type of Biomarker | Diagnostic |
| Pathway | Cell growth and/or maintenance, |
| Cohort | 204 (119 tumor and 85 non-tumor) HCC patients: HCV group (n=80), HBV group (n=19) and non-B, non-C group (n=20) |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | HCV and HBV - associated HCC and Non-HCV/HBV associated HCC |
| Year of Publication | 2006 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |