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The total number entries retrieved from this search are 378
Please click on Biomarker_ID to view detailed information.
Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2085Estrogen , Estradiol, AFPProtein + SteroidHumanDownregulated in liver cancer cell. DiagnosticNormal vs liver cancer p < 0.05Serum27060391
2086Estrone plus Estradiol/Testosterone ratioSteroidHumanDownregulated in liver cancer cell. DiagnosticNormal vs liver cancer p < 0.06Serum27060391
2087AFPProteinHumanDownregulated in liver cancer cell. DiagnosticNormal vs liver cancer p < 0.06Serum27060391
2089miR-200cmiRNAHumanDownregulated in PSC with control DiagnosticNormal v/s cancer v/s PSC p < 0.05Serum26864161
2090miR-483-5pmiRNAHumanUpregulated in CC compared with controls and PSC. DiagnosticNormal vs cancer p < 0.05Serum26864161
2091miR-194miRNAHumanUpregulated in CC compared with controls. DiagnosticNormal vs cancer p < 0.05Serum26864161
2093miR-122miRNAHumanUpregulatd in chronic HCV v/s healthy control (with log fold change 3.17) DiagnosticCancer v/s Normal p < 0.05Serum26812693
2094miR-222miRNAHumanUpregulatd in chronic HCV v/s healthy control (with log fold change 3.11) DiagnosticCancer v/s Normal p < 0.01Serum26812693
2095IRF1RNAsHumanUpregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticCancer v/s Normal FDR <0.01Cells26811688
2096GBP1RNAsHumanUpregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2097ICAM1RNAsHumanUpregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2098Foxa1RNAsHumanDownregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2099DHCR7RNAsHumanDownregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2100HMGCS2RNAsHumanDownregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2101MSMO1RNAsHumanDownregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) DiagnosticNormal vs HCC FDR <0.01Cells26811688
2103AFP-L3ProteinHumanUpregulated in AFP-negative HCC patients DiagnosticNormal vs HCC p < 0.01Tissue26770061
2104GP73ProteinHumanUpregulated in AFP-negative HCC patients DiagnosticNormal vs HCC p < 0.01Tissue26770061
2105AFP-L3, GP73 (combined)ProteinHumanUpregulated in AFP-negative HCC patients DiagnosticNormal vs HCC p < 0.01Tissue26770061
2106TOPO2ProteinHumanDownregulated in nucleolus of HCC DiagnosticNormal vs HCC NATissue26722553
2107Combination of S100A9 and GRNOthersHumanDownregulated in HCC patients Diagnostic and PrognosticNormal vs HCC p < 0.001Urine26675302
2108ABCC3ProteinRat and Humanoverexpressed in hepatocellular carcinoma Potential Diagnostic *Normal vs HCC p < 0.01Tissue26337276
2113Alpha-ketoglutaricMetaboliteHumanThe concentrations of α-KG in diabetic II and liver cancer urine samples were significantly lower than those from healthy people. DiagnosticNormal vs cancer p < 0.05Urine25871588
2114pyruvic acidMetaboliteHumanThe concentrations of PA in diabetic II and liver cancer urine samples were significantly lower than those from healthy people. DiagnosticNormal vs cancer p < 0.05Urine25871588
2117RNase AProteinHumanDownregulated in gastric cancer, liver cancer, pancreatic cancer, esophageal cancer, ovary cancer, cervical cancer, bladder cancer, kidney cancer and lung cancer DiagnosticCancer v/s Normal p < 0.01Serum24805924
2119KIAA1114ProteinHuman and Mice cell linesKIAA1114 is overexpressed in human liver cancer cell lines Potential Diagnostic *Normal cell line vs HCC cell line p < 0.05Tissue24713374
2126AFP (at a cut-off of 20 ng/mL)ProteinHumanUpregulated level in HCC DiagnosticHCC with cirrhosis v/s HCV-associated cirrhosis p < 0.05Serum24095974
2127DNA hypomethylated regions of GPM6BEpigenetic (Others)Humanhypomethylated and Upregulated level in HCC DiagnosticCancer v/s Normal p < 0.01Tissue23950870
2128DNA hypomethylated regions of MAGEA12Epigenetic (Others)Humanhypomethylated and Upregulated level in HCC DiagnosticCancer v/s Normal p < 0.01Tissue23950870
2129DNA hypomethylated regions of FCRL1Epigenetic (Others)Humanhypomethylated and Upregulated level in HCC DiagnosticInvasive HCC v/s non-invasive HCC p < 0.01Tissue23950870
2130VTNProteinHumanDownregulated in HCV-infected HCC patients DiagnosticNormal vs HCV-infected HCC patients, Normals vs non HCV-infected HCC p < 0.05Plasma23944848
2131SAPProteinHumanDownregulated in HCV-infected HCC patients DiagnosticNormal vs HCV-infected HCC patients, Normals vs non HCV-infected HCC p < 0.01Plasma23944848
2139C3ProteinMale Wistar ratsUpregulated at very early stage in HCC Potential Diagnostic *Normal vs HCC p < 0.05Tissue23245919
2140miR-18b*miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.21) DiagnosticNormal v/s HCC/HCV/HBV p < 0.001Tissue23205106
2141miR-296-5pmiRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.16) DiagnosticNormal v/s HCC/HCV/HBV p < 0.001Tissue23205106
2142miR-557miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.29) DiagnosticNormal v/s HCC/HCV/HBV p < 0.01Tissue23205106
2143miR-581miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.10) DiagnosticNormal v/s HCC/HCV/HBV p < 0.01Tissue23205106
2144miR-625*miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.23) DiagnosticNormal v/s HCC/HCV/HBV p < 0.01Tissue23205106
2145miR-1228miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.30) DiagnosticNormal v/s HCC/HCV/HBV p < 0.01Tissue23205106
2146miR-1249miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.20) DiagnosticNormal v/s HCC/HCV/HBV p < 0.001Tissue23205106
2147miR-2116*miRNAHumanDownregulated in the HCC v/s non-tumor (with fold change 0.048) DiagnosticNormal v/s HCC/HCV/HBV p < 0.05Tissue23205106
2148miR-129*miRNAHumanDownregulated in the HCC v/s non-tumor DiagnosticNormal vs HCC, liver cancer p < 0.05Tissue23205106
2149miR-146b-3pmiRNAHumanDownregulated in the HCC v/s non-tumor DiagnosticNormal vs HCC, liver cancer p < 0.05Tissue23205106
2150miR-448miRNAHumanDownregulated in the HCC v/s non-tumor DiagnosticNormal vs HCC, liver cancer p < 0.05Tissue23205106
2151DJ-1ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2152CAF-1ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2153HSP60ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2154DJ-1, CAF-1ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2155DJ-1, HSP60ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2156CAF-1, HSP60ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380
2157DJ-1, CAF-1, HSP60ProteinHumanUpregulated in HCC DiagnosticNormal vs HCC with Hepatitis C and without Hepatitis C p < 0.05Urine23074380

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