Detailed information |
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CancerLivER ID | 2094 |
Biomarker | miR-222 |
Biomarker Name/Symbol (given in Publication) | miR-222 (at a cutoff value of 1.405) |
Biomolecule | miRNA |
Subject | Human |
Degree of Validity | Potential biomarker of chronic HCV; but not validated on independent dataset |
Experimental Condition | Cancer v/s Normal |
Cancer type | HCV (Hepatitis C Viral infection) |
Regulation | Upregulatd in chronic HCV v/s healthy control (with log fold change 3.11) |
Level of significance | p < 0.01 |
Source | Serum |
PMID | 26812693 |
Type of Biomarker | Diagnostic |
Pathway | Signaling pathways ,CDK4 translation |
Cohort | 40 patients with chronic HCV (male = 28 and female = 12) and 60 patients with liver cancer (male = 50 and female = 10) and 30 matched healthy controls. |
Sensitivity | 80 % |
Specificity | 90% |
Accuracy | NA |
AUC | 0.804 (95 % CI 0.689-0.919) |
Disease | Human HCV |
Year of Publication | 2016 |
Clinical trial | YES |
NCT No# (Clinical trial) | NCT02928627 |