CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2128
Detailed information
CancerLivER ID2128
BiomarkerDNA hypomethylated regions of MAGEA12
Biomarker Name/Symbol (given in Publication)DNA hypomethylated regions of MAGEA12
BiomoleculeEpigenetic (Others)
SubjectHuman
Degree of ValidityBiomarkers for liver cancer diagnosis and prognosis, especially in populations with high risk for HCC development and validated on independent dataset
Experimental ConditionCancer v/s Normal
Cancer typeHepatocellular carcinoma
Regulationhypomethylated and Upregulated level in HCC
Level of significance p < 0.01
SourceTissue
PMID23950870
Type of BiomarkerDiagnostic
Pathwaymember of oncogenic MAGE family,
CohortTraining dataset: 12 patients with HCC and 1 with inflammatory pseudotumor; Validation dataset: cohort consisted of 4 HCC patients and 4 CHB patients
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHuman HCC
Year of Publication2013
Clinical trialNO
Clinical trial (NCT Number)NA

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