CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2090
Detailed information
CancerLivER ID2090
Biomarker miR-483-5p
Biomarker Name/Symbol (given in Publication)miR-483-5p
BiomoleculemiRNA
SubjectHuman
Degree of ValidityBiomarkers for the diagnosis of PSC and validated on independent daatset
Experimental ConditionNormal vs cancer
Cancer typeCholangiocarcinoma
RegulationUpregulated in CC compared with controls and PSC.
Level of significance p < 0.05
SourceSerum
PMID26864161
Type of BiomarkerDiagnostic
Pathwaynuclear factor kappa B (NF-jB) signalling pathway;
CohortTraining dataset contain 90 human serum samples (30 PSC (primary sclerosing cholangitis), 30 CC and 30 control subjects); and validation dataset contain 140 samples [40 PSC, 40 CC, 20 primary biliary cirrhosis (PBC) and 40 controls]
SensitivityNA
SpecificityNA
AccuracyNA
AUCAUC > 0.70
DiseaseHuman PSC, CC
Year of Publication2016
Clinical trialNO
Clinical trial (NCT Number)NA

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