| Detailed information |
|---|
| CancerLivER ID | 2090 |
| Biomarker | miR-483-5p |
| Biomarker Name/Symbol (given in Publication) | miR-483-5p |
| Biomolecule | miRNA |
| Subject | Human |
| Degree of Validity | Biomarkers for the diagnosis of PSC and validated on independent daatset |
| Experimental Condition | Normal vs cancer |
| Cancer type | Cholangiocarcinoma |
| Regulation | Upregulated in CC compared with controls and PSC. |
| Level of significance | p < 0.05 |
| Source | Serum |
| PMID | 26864161 |
| Type of Biomarker | Diagnostic |
| Pathway | nuclear factor kappa B (NF-jB) signalling pathway; |
| Cohort | Training dataset contain 90 human serum samples (30 PSC (primary sclerosing cholangitis), 30 CC and 30 control subjects); and validation dataset contain 140 samples [40 PSC, 40 CC, 20 primary biliary cirrhosis (PBC) and 40 controls] |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | AUC > 0.70 |
| Disease | Human PSC, CC |
| Year of Publication | 2016 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |