| Detailed information |
|---|
| CancerLivER ID | 2100 |
| Biomarker | HMGCS2 |
| Biomarker Name/Symbol (given in Publication) | HMGCS2 |
| Biomolecule | RNAs |
| Subject | Human |
| Degree of Validity | Biomarkers of JFH-1-infected HCC and validated on independent dataset |
| Experimental Condition | Normal vs HCC |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Downregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) |
| Level of significance | FDR <0.01 |
| Source | Cells |
| PMID | 26811688 |
| Type of Biomarker | Diagnostic |
| Pathway | cholesterol biosynthesis pathway.5 |
| Cohort | Cell lines:GSE20948 includes 14 JFH-1-infected (Japanese fulminant hepatitis-1) Huh7 cell samples and 14 mock-infected Huh7 cell samples; validation datasetss: miRNASeq (including 372 HCC samples and 50 control samples) and RNASeq V2 (including 371 HCC samples and 50 control samples) were downloade |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2016 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |