CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2100
Detailed information
CancerLivER ID2100
Biomarker HMGCS2
Biomarker Name/Symbol (given in Publication)HMGCS2
BiomoleculeRNAs
SubjectHuman
Degree of ValidityBiomarkers of JFH-1-infected HCC and validated on independent dataset
Experimental ConditionNormal vs HCC
Cancer typeHepatocellular carcinoma
RegulationDownregulated in JFH-1-infected Huh7 cells (with log fold change more than 1)
Level of significance FDR <0.01
SourceCells
PMID26811688
Type of BiomarkerDiagnostic
Pathwaycholesterol biosynthesis pathway.5
CohortCell lines:GSE20948 includes 14 JFH-1-infected (Japanese fulminant hepatitis-1) Huh7 cell samples and 14 mock-infected Huh7 cell samples; validation datasetss: miRNASeq (including 372 HCC samples and 50 control samples) and RNASeq V2 (including 371 HCC samples and 50 control samples) were downloade
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHuman HCC
Year of Publication2016
Clinical trialNO
Clinical trial (NCT Number)NA

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