| Detailed information |
|---|
| CancerLivER ID | 2126 |
| Biomarker | AFP (at a cut-off of 20 ng/mL) |
| Biomarker Name/Symbol (given in Publication) | AFP (at a cut-off of 20 ng/mL) |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | It detects HCC with a high level of accuracy in patients with cirrhosis and HIV infection and validated on independent dataset |
| Experimental Condition | HCC with cirrhosis v/s HCV-associated cirrhosis |
| Cancer type | Hepatocellular carcinoma, Cirrhosis |
| Regulation | Upregulated level in HCC |
| Level of significance | p < 0.05 |
| Source | Serum |
| PMID | 24095974 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | 452 Patients having cirrhosis with HCC and 676 Patients having cirrhosis without HCC |
| Sensitivity | 70.10% |
| Specificity | 89.80% |
| Accuracy | 83% |
| AUC | NA |
| Disease | Human HCC, Cirrhosis |
| Year of Publication | 2014 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT00005629,NCT03132792,NCT00513461,NCT00093548,NCT01350167,NCT02435433,NCT02072356,NCT02582918,NCT02232490,NCT01128803,NCT02312817,NCT01849588,NCT03156582,NCT03533582,NCT03767764,NCT01078311,NCT03493763,NCT00980460,NCT00629421,NCT01392131,NCT0174764 |