CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2156
Detailed information
CancerLivER ID2156
Biomarker CAF-1, HSP60
Biomarker Name/Symbol (given in Publication)CAF-1 and HSP60
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential new biomarkers that are able to predict HCC development at earlier stages and validated on independent dataset
Experimental ConditionNormal vs HCC with Hepatitis C and without Hepatitis C
Cancer typeHepatocellular carcinoma
RegulationUpregulated in HCC
Level of significance p < 0.05
SourceUrine
PMID23074380
Type of BiomarkerDiagnostic
PathwayP13K-Akt-PKB
CohortTraining Dataset:106 Hepatitis C infected patients patients, 32 of whom had already developed Hepatocellular Carcinoma; Validation dataset: 74 patients who were diagnosed as Hepatocellular Carcinoma -free at the time of initial sample collection,12 healthy control individuals
Sensitivity92%
Specificity61%
Accuracy77%
AUCNA
DiseaseHuman HCC
Year of Publication2012
Clinical trialNO
Clinical trial (NCT Number)NA

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