Detailed information |
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CancerLivER ID | 2095 |
Biomarker | IRF1 |
Biomarker Name/Symbol (given in Publication) | IRF1 |
Biomolecule | RNAs |
Subject | Human |
Degree of Validity | Biomarkers of JFH-1-infected HCC and validated on independent dataset |
Experimental Condition | Cancer v/s Normal |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in JFH-1-infected Huh7 cells (with log fold change more than 1) |
Level of significance | FDR <0.01 |
Source | Cells |
PMID | 26811688 |
Type of Biomarker | Diagnostic |
Pathway | cholesterol biosynthesis pathway.5 |
Cohort | Cell lines:GSE20948 includes 14 JFH-1-infected (Japanese fulminant hepatitis-1) Huh7 cell samples and 14 mock-infected Huh7 cell samples; validation datasetss: miRNASeq (including 372 HCC samples and 50 control samples) and RNASeq V2 (including 371 HCC samples and 50 control samples) were downloade |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2016 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |