CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2103
Detailed information
CancerLivER ID2103
Biomarker AFP-L3
Biomarker Name/Symbol (given in Publication)AFP-L3
BiomoleculeProtein
SubjectHuman
Degree of ValidityBiomarkers for diagnosing alpha- fetoprotein-negative hepatocellular carcinoma and validated on independent dataset
Experimental ConditionNormal vs HCC
Cancer typeHepatocellular carcinoma
RegulationUpregulated in AFP-negative HCC patients
Level of significance p < 0.01
SourceTissue
PMID26770061
Type of BiomarkerDiagnostic
PathwayNA
Cohort50 AFP-negative HCC patients from the Qianfoshan Hospital in Shandong province to participate in this study, a group of 50 healthy subjects (31 men and 19 women; mean age 42 years; range 20 to 68 years) from the same hospital to serve as controls.
Sensitivity50.00%
Specificity97.50%
Accuracy79.20%
AUCNA
DiseaseHuman HCC
Year of Publication2015
Clinical trialYES
NCT No# (Clinical trial) NCT00687596

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