| Detailed information |
|---|
| CancerLivER ID | 2103 |
| Biomarker | AFP-L3 |
| Biomarker Name/Symbol (given in Publication) | AFP-L3 |
| Biomolecule | Protein |
| Subject | Human |
| Degree of Validity | Biomarkers for diagnosing alpha- fetoprotein-negative hepatocellular carcinoma and validated on independent dataset |
| Experimental Condition | Normal vs HCC |
| Cancer type | Hepatocellular carcinoma |
| Regulation | Upregulated in AFP-negative HCC patients |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 26770061 |
| Type of Biomarker | Diagnostic |
| Pathway | NA |
| Cohort | 50 AFP-negative HCC patients from the Qianfoshan Hospital in Shandong province to participate in this study, a group of 50 healthy subjects (31 men and 19 women; mean age 42 years; range 20 to 68 years) from the same hospital to serve as controls. |
| Sensitivity | 50.00% |
| Specificity | 97.50% |
| Accuracy | 79.20% |
| AUC | NA |
| Disease | Human HCC |
| Year of Publication | 2015 |
| Clinical trial | YES |
| NCT No# (Clinical trial) | NCT00687596 |