Detailed information |
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CancerLivER ID | 2152 |
Biomarker | CAF-1 |
Biomarker Name/Symbol (given in Publication) | CAF-1 |
Biomolecule | Protein |
Subject | Human |
Degree of Validity | Potential new biomarkers that are able to predict HCC development at earlier stages and validated on independent dataset |
Experimental Condition | Normal vs HCC with Hepatitis C and without Hepatitis C |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in HCC |
Level of significance | p < 0.05 |
Source | Urine |
PMID | 23074380 |
Type of Biomarker | Diagnostic |
Pathway | P13K-Akt-PKB |
Cohort | Training Dataset:106 Hepatitis C infected patients patients, 32 of whom had already developed Hepatocellular Carcinoma; Validation dataset: 74 patients who were diagnosed as Hepatocellular Carcinoma -free at the time of initial sample collection,12 healthy control individuals |
Sensitivity | 90% |
Specificity | 66% |
Accuracy | 78% |
AUC | NA |
Disease | Human HCC |
Year of Publication | 2012 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |