CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2483
Detailed information
CancerLivER ID2483
Biomarker MYO1D, EST, PDGF-B, LOC113246, SPTAN1, MGC19556, IL6R, PRPSAP1, PDCD6IP, AHNAK, BCL2L11, GPAA1, c-fos, SLC11A2, LOC51235, PRPF8, CD36L1, KIAA1055, HNRPDL, NDRG1, NARS, PABPC4, RDBP, CALM2, PDCD6, C1R, ALB, MT1G, CED-6, AMACR, A2M, FGG, SUPV3L1, PHLDA1, NBP, HAMP, HCS, KIAA0635, ECHS1, SHMT1, NNMT, A
Biomarker Name/Symbol (given in Publication)61 genes signature (MYO1D, EST, PDGF-B, LOC113246, SPTAN1, MGC19556, IL6R, PRPSAP1, PDCD6IP, AHNAK, BCL2L11, GPAA1, c-fos, SLC11A2, LOC51235, PRPF8, CD36L1, KIAA1055, HNRPDL, NDRG1, NARS, PABPC4, RDBP, CALM2, PDCD6, C1R, ALB, MT1G, CED-6, AMACR, A2M, FGG, SUPV3L1, PHLDA1, NBP, HAMP, HCS, KIAA0635, ECHS1, SHMT1, NNMT, A1BG, ZNF297B, MAWBP, BCL2L1, FGB, HABP2, SLC6A5, SEMA5A, PROL2, EST, GRLF1, LABH3, AQP3, STATI2, p21, IGFBP3, FABP1, STK39, CP, DVL1)
BiomoleculeRNAs
SubjectHuman
Degree of ValidityPotential Diagnostic marker for HCC and validated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDifferentially expressed between HCC and non-tumor liver tissue
Level of significance p < 0.01
SourceTissue
PMID14642619
Type of BiomarkerDiagnostic
PathwayNA
CohortTraining dataset: 68 non-B, non-C liver samples, including 20 T and 17 NT samples, that were obtained from non-B, non-C HCC patients, and 31 N samples from metastatic liver cancer patients; Validation dataset: 37 non-B, non-C liver tissues (20 HCC, 17 non-tumor liver) from 20 patients
SensitivityNA
SpecificityNA
Accuracy90.00%
AUC
DiseaseHCC v/s non-tumor
Year of Publication2003
Clinical trialNO
Clinical trial (NCT Number)NA

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