CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2513
Detailed information
CancerLivER ID2513
Biomarker OTC
Biomarker Name/Symbol (given in Publication)ornithine carbamoyl transferase (OTC)
BiomoleculeProtein
SubjectHuman
Degree of ValidityPotential diagnostic marker for HCC; but not validated on independent dataset
Experimental ConditionHCC v/s non-tumor
Cancer typeHepatocellular carcinoma
RegulationDownregulated in HCC than non-tumor (with > 3 fold change)
Level of significance p < 0.05
SourceTissue
PMID18715028
Type of BiomarkerDiagnostic
PathwayAmino acid metabolism
Cohort56 HCC: 13 metastatic tissues along with 46 poor to well differentiated hepatocellular carcinoma from patients in the age group of 40 to 72 years and 59 noncancer tissues; The tissue microarrays from Creative Biolabs consisted of 15 well differentiated, 29 moderately differentiated, and 12 poorly di
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHCC v/s non-tumor
Year of Publication2008
Clinical trialNO
Clinical trial (NCT Number)NA

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