A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1005 | Th1002 | Cetuximab | Heavy chain:QVQLKQSG Full view | 243 | IIIc | Cancer | Erbitux | ImClone Systems Inc | Sterile, clear, colorless liquid of pH 7.0-7.4, which may contain a small amount of easily visible, white, amorphous cetuximab particulates | Intravenous infusion | Antineoplastic Agents | Epidermal growth factor receptor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
1022 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Pulmozyme | Genentech Inc | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
1023 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Viscozyme | Roche (Chile) | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
1025 | Th1004 | Denileukin diftitox | MGADDVVDSSKSFVMENFSS Full view | 255 | IIb | Cancer | Ontak | Seragen Inc | Sterile, white, preservative-free, lyophilized powder. | Intravenous(IV) administration | Antineoplastic Agents | Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Cytokine receptor common subunit gamma |
1028 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel | Immunex Corp | Lyophilized powder. | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
1029 | Th1005 | Etanercept | LPAQVAFTPYAPEPGSTCRL Full view | 255 | IIa | Immunological | Enbrel Sureclick | N.A. | Solution | Subcutaneous injection | Immunosuppressive Agents | Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re |
1055 | Th1009 | Alteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | Activase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous | Thrombolytic Agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1067 | Th1012 | Reteplase | SYQGNSDCYFGNGSAYRGTH Full view | 255 | Ib | Hematological,Metabolic | Retavase | Centocor | Sterile, white, lyophilized powder | Intravenous Injection | Fibrinolytic Agents, Thrombolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1110 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon | Interferon Sciences Inc. | Solution | Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1111 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon LDO | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1112 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon N Injection | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1142 | Th1020 | Asparaginase | QMSLQQELRYIEALSAIVET Full view | 255 | Ic | Cancer | Elspar | Merck & Co. Inc | Lyophilized plug or powder | Intravenous or Intramuscular. Intravenous method dose has higher risk of allergic reaction, so often a test dose is given first. | Antineoplastic Agents | L-asparagine |
1145 | Th1021 | Thyrotropin Alfa | Alpha chain:APDVQDC< Full view | 204 | IV | Cancer | Thyrogen | Genzyme Inc | Lyophilized powder | Intramuscular preferably the buttocks | Diagnostic Agents | Thyrotropin receptor |
1148 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Advate | N.A. | Powder form | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1149 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Alphanate | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1150 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Bioclate | Baxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc. | Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powder | Intravenous infusion | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1151 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Helixate FS | N.A. | Sterile, stable, purified, nonpyrogenic, dried concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1152 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hemofil M | N.A. | Dry concentrate | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1153 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Hyate:C | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1154 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Koate-HP | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1155 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Kogenate FS | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1156 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monarc-M | N.A. | Powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1157 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Monoclate-P | N.A. | Lyophilized powder for solution | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1158 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | ReFacto | N.A. | Lyophilized powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1159 | Th1022 | Antihemophilic Factor | ATRRYYLGAVELSWDYMQSD Full view | 255 | Ia | Hematological,Metabolic | Xyntha | N.A. | Sterile, nonpyrogenic, preservative-free, freeze-dried powder | Intravenous Injection | Coagulants and Thrombotic agents | Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2 |
1193 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Civacir | N.A. | N.A. | N.A. | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1194 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Flebogamma | Instituto Grifols SA | Sterile, clear or slightly opalescent and colorless to pale yellow, liquid | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1195 | Th1025 | Intravenous Immunoglobulin | IGG1:PSALTQPPSASGSLG Full view | 250 | Ia | Immunological | Gamunex | Talecris Biotherapeutics | Sterile solution | Intravenous infusion | Immunosuppressive Agents, Immunologic factors, Anti-infective agents | High affinity immunoglobulin gamma Fc receptor I,High affinity immunoglobulin gamma Fc receptor IB,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc reg |
1201 | Th1026 | Anistreplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ic | Hematological,Metabolic | Eminase | Wulfing Pharma GmbH | Dry powder | Intravenous infusion | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
1210 | Th1028 | Tenecteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | TNKase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous Injection | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein |
1215 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Menopur | N.A. | Sterile, lyophilized powder which is reconstitution with sterile 0.9% Sodium Chloride Injection. | Subcutaneous Injection | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
1216 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Repronex | N.A. | Sterile, lyophilized form | Subcutaneous or Intramuscular Injection. | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
1234 | Th1032 | Coagulation factor VIIa | ANAFLEELRPGSLERECKEE Full view | 255 | Ib | Hematological,Metabolic | NovoSeven | Novo Nordisk | Sterile, white lyophilized powder | Injection | Thrombotic Agents, Coagulants | Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor |
1260 | Th1037 | Botulinum Toxin Type B | MPVTINNFNYNDPIDNNNII Full view | 255 | Ic | Neurological Disorder | Myobloc | Solstice Neurosciences | Clear and colorless to light-yellow sterile injectable solution | Injection | Antidystonic Agents | Vesicle-associated membrane protein 2,Vesicle-associated membrane protein 1,Synaptotagmin-2 |
1261 | Th1037 | Botulinum Toxin Type B | MPVTINNFNYNDPIDNNNII Full view | 255 | Ic | Neurological Disorder | Neurobloc | Solstice Neurosciences | Clear and colourless to light yellow solution | Intramuscular Injection | Antidystonic Agents | Vesicle-associated membrane protein 2,Vesicle-associated membrane protein 1,Synaptotagmin-2 |
1265 | Th1038 | Omalizumab | Heavy chain:EVQLVESG Full view | 243 | IIa | Immunological | Xolair | Genentech Inc | Sterile, white, preservative free, lyophilized powde | Subcutaneous Injection | Anti-Allergic Agents, Anti-asthmatic, Immuno-suppressive agents | High affinity immunoglobulin epsilon receptor subunit alpha and beta |
1269 | Th1039 | Lutropin alfa | Alpha Chain: APDVQDC Full view | 213 | Ib | Hormonal | Luveris | Serono | White lyophilised pellet withg clear colourless solvent to make solution | Subcutaneous (SC) administration | Fertility Agents | Lutropin-choriogonadotropic hormone receptor |
1288 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Cordase | N.A. | N.A. | N.A. | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1289 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Santyl | Advance Biofactures Corp | Sterile enzymatic debriding ointment | External use only | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1290 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Xiaflex | Auxilium | Sterile lyophilized powder (white cake) | Intralesional Injection | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1305 | Th1043 | Rasburicase | SAVKAARYGKDNVRVYKVHK Full view | 255 | Ic | Metabolic/Genetic | Elitek | Sanofi-Synthelabo Inc | Sterile, white to off-white, lyophilized powder | Intravenous administration | Antihyperuricemic Agents, Gout suppressants | Uric acid |
1306 | Th1043 | Rasburicase | SAVKAARYGKDNVRVYKVHK Full view | 255 | Ic | Metabolic/Genetic | Fasturtec | N.A. | Powder and solvent that are made upto make solution. | Intravenous administartion | Antihyperuricemic Agents, Gout suppressants | Uric acid |
1316 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Immunological | Humira | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous administration | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1317 | Th1044 | Adalimumab | Light-chain:DIQMTQS< Full view | 230 | Ic | Osteological | Humira Pen | Abbott Laboratories | Sterile, preservative-free solution | Subcutaneous injection | Immunosuppressive Agents, Anti-inflammatory, Antirheumatic agents | Tumor necrosis factor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamm |
1324 | Th1045 | Imiglucerase | ARPCIPKSFGYSSVVCVCNA Full view | 255 | Ia | Metabolic | Cerezyme | Genzyme | Sterile, non-pyrogenic, white to off-white lyophilized product | Intravenous infusion | Enzyme Replacement Agents | Glucocerebroside |
1327 | Th1046 | Abciximab | H ReoPro-like antibo Full view | 218 | IIa | Genetic/Metabolic/Haemetological | ReoPro | Eli Lilly and Company | Clear, colorless, sterile, non-pyrogenic solution | Intravenous administartion | Platelet Aggregation Inhibitors, Anticoagulants | Integrin beta-3,Integrin alpha-IIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immuno |
1331 | Th1047 | Alpha-1-proteinase inhibitor | EDPQGDAAQKTDTSHHDQDH Full view | 255 | IIa | Metabolic/Geneti/Respiratory | Aralast | Baxter | Lyophilized powder | Intravenous infusion | Serine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors | Neutrophil elastase |
1332 | Th1047 | Alpha-1-proteinase inhibitor | EDPQGDAAQKTDTSHHDQDH Full view | 255 | IIa | Metabolic/Geneti/Respiratory | Prolastin | Talecris Biotherapeutics C formerly Bayer | Lyophilized powder | Intravenous infusion | Serine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors | Neutrophil elastase |
1337 | Th1048 | Pegaspargase | MEFFKKTALAALVMGFSGAA Full view | 255 | Ic | Cancer | Oncaspar | Enzon Inc | Solution | Intravenous or Intramuscular administration | Antineoplastic Agents | L-asparagine |
1358 | Th1050 | Pegademase bovine | MAQTPAFNKPKVELHVHLDG Full view | 255 | Ia | Metabolic | Adagen | Enzon Inc. | Isotonic, pyrogen free, sterile solution, pH 7.2-7.4 | Intramusular Injection | Enzyme Replacement Agents | Adenosine,Growth factor receptor-bound protein 2 |