Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID1001 | SequenceACSSSPSKHCG | NameTD1 | Nature of peptide or cargoTD1 enhances the transdermal delivery of macromolecules | AssayFranz diffusion cells | Tissue permeabilitySignificant increase in permeability of the peptide can be seen by the addition of ATP.The amount of protein that permeated the skin was determined with ELISA | Tissue SampleMale SD rats skin cells | PUBMED ID25269793 |
| ID1020 | SequenceACSSSPSKHCG | NameTDN | Nature of peptide or cargoTD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | AssayConfocal Laser Scanning Microscopy | Tissue permeabilitySignificant permeability of the peptide can be seen in confocal images | Tissue SampleMale SD rats skin cells | PUBMED ID23391375 |
| ID1021 | SequenceACSSKKSKHCG | NameTD-34 | Nature of peptide or cargoTD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | AssayConfocal Laser Scanning Microscopy | Tissue permeabilitySignificant permeability of the peptide can be seen in confocal images | Tissue SampleMale SD rats skin cells | PUBMED ID23391375 |
| ID1022 | SequenceACSSSPSKHCG | NameTD1 | Nature of peptide or cargoTD1 enhances the transdermal delivery of macromolecules | AssayFranz diffusion cells, immunity fluorescence techniques | Tissue permeabilitySignificant permeability of the peptide can be seen. The amount of protein that permeated the skin was determined with immunity fluorescence techniques | Tissue SampleMale SD rats skin cells | PUBMED ID23385091 |
| ID1096 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayFluorescence microscopy, Transmission electron microscopy | Tissue permeabilityPenetrates to the stratum corneum of rat footpad 15 min after topical application. | Tissue SampleFootpad skin of rats | PUBMED ID22009459 |
| ID1097 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayFluorescence microscopy, Transmission electron microscopy | Tissue permeabilityCo-administered FAM-labeled siRNA gathered in the hair follicle 30 min after application | Tissue SampleBack skin of rats | PUBMED ID22009459 |
| ID1098 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayFluorescence microscopy, Transmission electron microscopy | Tissue permeabilityFAM-labeled siRNA and TD-1 topically co-administered penetrated from the stratum corneum to subcutaneous tissue 15 min after application | Tissue SampleFootpad skin of rats | PUBMED ID22009459 |
| ID1099 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayFluorescence microscopy, Transmission electron microscopy | Tissue permeabilityTD1 detected strongly from epithelial tissue to subcutaneous tissue 60 min after application | Tissue SampleFootpad skin of rats | PUBMED ID22009459 |
| ID1100 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayFluorescence microscopy, Transmission electron microscopy | Tissue permeabilityBoth FITC-labeled TD-1 and co-administered FAM-labeled siRNA were detected strongly from epithelial tissue to subcutaneous tissue 60 min after application | Tissue SampleFootpad skin of rats | PUBMED ID22009459 |
| ID1101 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayRT-PCR | Tissue permeabilityThe level of GADPH decreased 37 % | Tissue SampleRat footpad skin | PUBMED ID22009459 |
| ID1102 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTransdermal Delivery enhancer | AssayRT-PCR | Tissue permeabilityThe level of GADPH decreased 49 % | Tissue SampleRat footpad skin | PUBMED ID22009459 |
| ID1107 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTD1 enhances the transdermal delivery of macromolecules | AssayElectrical stimulation of the saphenous nerve at 4 Hz for 1 min in skin pretreated with vehicle | Tissue permeabilityThe maximum amount of PE (Plasma Extravasation) in the control side was 68 ± 3 PIUs compared to 46 ± 2 PIUs in BoNT-A + TD-1 pretreated skin | Tissue SampleDorsal surface of the rat hindpaw skin | PUBMED ID20223589 |
| ID1111 | SequenceGRKKRRQRRRPPQ | NameTat | Nature of peptide or cargoCell penetrating peptide | AssayFranz cell system | Tissue permeabilityKp (permeability coefficients) 6.30 in the cubic system | Tissue SamplePorcine skin | PUBMED ID19733297 |
| ID1112 | SequenceGRKKRRQRRRPPQ | NameTat | Nature of peptide or cargoCell penetrating peptide | AssayFranz cell system | Tissue permeabilityKp (permeability coefficients) 1.70 in the cubic system | Tissue SamplePorcine skin | PUBMED ID19733297 |
| ID1141 | SequenceACSSSPSKHCG | NameTD-1 | Nature of peptide or cargoTD1 enhances the transdermal delivery of macromolecules | AssayConfocal Laser Scanning Microscopy, Blood glucose measurement | Tissue permeabilitySignificant permeability of insulin could be seen in the confocal images, TD-1 without insulin had no effect on either blood glucose or serum insulin level, indicating that the glucose-lowering effect observed with TD 1 and insulin coadministration was due to the delivered exogenous insulin and not a physiological response elicited by TD-1 | Tissue SampleAbdominal skin of rat | PUBMED ID16565728 |
| ID1142 | SequenceLNQEQVSPRKKC | NamePeptide | Nature of peptide or cargoPeptide containing α 2-plasmin inhibitor fibrin-binding site to the free amines on the surface of the KGF molecule | AssayInverted fluorescence microscopy | Tissue permeabilityThe gradual healing of wound coould be easily visualised in th fluoresence microscopy images. Overlaid fluorescent and bright-field images of the wound show migrating cells as they degrade the fibrin matrix | Tissue SampleHuman skin equivalents were grafted to athymic mice | PUBMED ID16314471 |
| ID1144 | SequenceTSLDASIIWAMMQN | NameP144 | Nature of peptide or cargoInterferes with TGF-β1 binding to its cellular receptors on Mv1Lu cells. Potent in vivo anti-fibrotic activity in the liver of rats receiving CCl4 | AssaySircol Collagen Assay kit, histological and immunohistochemical studies | Tissue permeabilityDermal thickness: Bleomycin treated-180%, Bleomycin plus P144 lipogel emulsion-120%, Bleomycin plus vehicle-200%. Soluble collagen: Bleomycin treated-215%, Bleomycin plus P144 lipogel emulsion-150%, Bleomycin plus vehicle-220%. Data represent mean±SD of 10 mice per group, and the values of PBS-treated mice are set to 100%. | Tissue SampleShaved skin area of female C3H mice | PUBMED ID16117784 |
| ID1152 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.12 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1153 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.054 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1154 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.02 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1155 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.06 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1156 | SequenceYKALRISRKLAK | NameYKAc | Nature of peptide or cargoIt is a nontransducing peptide | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1157 | SequenceWLRRASAPLPGLK | NameP20 | Nature of peptide or cargoPhosphopeptide analogue of the heat shock protein (HSP) 20 | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.1 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1158 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.04 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1159 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.05 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1160 | SequenceYKALRISRKLAK | NameYKAc | Nature of peptide or cargoIt is a nontransducing peptide | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1161 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.046 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1162 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.055 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1163 | SequenceYKALRISRKLAK | NameYKAc | Nature of peptide or cargoIt is a nontransducing peptide | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1164 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.048 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1165 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0.056 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1166 | SequenceYKALRISRKLAK | NameYKAc | Nature of peptide or cargoIt is a nontransducing peptide | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityTransdermal delivery(nmol)- -̴0 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1167 | SequenceWLRRASAPLPGLK | NameP20 | Nature of peptide or cargoPhosphopeptide analogue of the heat shock protein (HSP) 20 | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.15 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1168 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.6 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1169 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.7 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1170 | SequenceWLRRASAPLPGLK | NameP20 | Nature of peptide or cargoPhosphopeptide analogue of the heat shock protein (HSP) 20 | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.05 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1171 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.9 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1172 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.98 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1173 | SequenceWLRRASAPLPGLK | NameP20 | Nature of peptide or cargoPhosphopeptide analogue of the heat shock protein (HSP) 20 | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.13 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1174 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.39 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1175 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.47 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1176 | SequenceWLRRASAPLPGLK | NameP20 | Nature of peptide or cargoPhosphopeptide analogue of the heat shock protein (HSP) 20 | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.01 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1177 | SequenceYARAAARQARA | NameYARA | Nature of peptide or cargoMolecular modification of TAT has led to the discovery of a new, optimized PTD, YARA which can penetrate intact strips of porcine coronary artery and human saphenous vein smooth muscle. | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.03 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1178 | SequenceYGRKKRRQRRR | NameTAT | Nature of peptide or cargoHIV transcription factor TAT which is a protein transduction domain characterized by a high content of positively charged arginine and lysine amino acid residues | AssayFluorimetry analysis using Gemini SpectraMax plate reader | Tissue permeabilityRate of skin penetration(nmol/cm2/h)- -̴0.1 | Tissue SampleFreshly excised porcine ear skin's stratum corneum (facing the donor compartment) was mounted in a Franz diffusion cell | PUBMED ID15906170 |
| ID1179 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Depth of wound crater(mm)=1.35/2.0(control), Wound necrosis area(mm2)=16/27(control), Wound area(mm2)=87.5/100(control), Oedema (µm)=975/1175(control), No. of blood vessels=3/2(control), Diameter of blood vessels (µm)=900/1000(control), No. of inflammatory cells=73.5/116(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |
| ID1180 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Depth of wound crater(mm)=1.85/2.0(control), Wound necrosis area(mm2)=20/27(control), Wound area(mm2)=97.5/100(control), Oedema (µm)=1100/1175(control), No. of blood vessels=2/2(control), Diameter of blood vessels (µm)=875/1000(control), No. of inflammatory cells=103.5/116(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |
| ID1181 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Depth of wound crater(mm)=2.05/2.0(control), Wound necrosis area(mm2)=24.5/27(control), Wound area(mm2)=100/100(control), Oedema (µm)=1150/1175(control), No. of blood vessels=2/2(control), Diameter of blood vessels (µm)=875/1000(control), No. of inflammatory cells=123/116(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |
| ID1182 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Wound area(mm2)=80/100(control), No. of blood vessels=2/0(control), Diameter of blood vessels (µm)=105/110(control), Reticulin (%)=51/21.5(control), Collagen (%)=70.5/39.5(control), Necrosis (score 0–4)=2/3(control), No. of vital follicles=58.5/20(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |
| ID1183 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Wound area(mm2)=97.5/100(control), No. of blood vessels=1/0(control), Diameter of blood vessels (µm)=55/110(control), Reticulin (%)=31/21.5(control), Collagen (%)=43.5/39.5(control), Necrosis (score 0–4)=3/3(control), No. of vital follicles=34/20(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |
| ID1184 | SequenceGEPPPGKPADDAGLV | NamePentadecapeptide BPC157 | Nature of peptide or cargoIt consistently improves burn healing, counteract the impairment of burn healing induced by systemic corticosteroids, promotes healing in ulcers and wounds with remarkable stability. | AssayMacroscopically, gross lesion severity was gauged by the depth of the wound crater (mm), the area of necrosis and the wound area. Microscopically, the factors investigated included oedema, blood vessel formation and their total diameter, the number of preserved hair follicles, reticulin and collagen formation. | Tissue permeabilityParameters studied: Wound area(mm2)=97.5/100(control), No. of blood vessels=0.5/0(control), Diameter of blood vessels (µm)=40/110(control), Reticulin (%)=26/21.5(control), Collagen (%)=31.5/39.5(control), Necrosis (score 0–4)=3/3(control), No. of vital follicles=26/20(control) | Tissue SampleRandomly assigned male mice (NMRI–Hannover) were used to create an injury on the dorsal skin | PUBMED ID15774286 |